Reactive oxygen species (ROS) are produced in cells during metabolic processes.
Excessive intracellular ROS may react with large biomolecules, such as DNA, RNA …

Oxidative stress due to imbalance between ROS production and detoxification plays a
pivotal role in determining cell fate. In response to the excessive ROS, apoptotic signaling …

The toxicity of misfolded proteins and mitochondrial dysfunction are pivotal factors that
promote age-associated functional neuronal decline and neurodegenerative disease …

The walnut (Juglans spp.) is an appreciated nut that belongs to the Juglandaceae family.
The fruit includes four main parts: the kernel, the skin, the shell, and the green husk. It is …

Juglone (5-hydroxyl-1, 4-naphthoquinone) is a phenolic compound found in walnuts.
Because of the antioxidant capacities of phenolic compounds, juglone may serve to combat …

Grape polyphenols have previously been shown to improve gut health and attenuate the
symptoms of metabolic syndrome; however, the mechanism of these beneficial effects is still …

Cancer cells produce high levels of reactive oxygen species (ROS) that lead to a state of
increased basal oxidative stress. Since this state of oxidative stress makes cancer cells …

Abstract Juglone (5-hydroxy-1, 4-naphthalene diketone) is a kind of natural
naphthoquinone, present in the roots, leaves, nut-hulls, bark and wood of walnut trees …

As an innovative treatment strategy for cancer treatment, Fenton reaction-mediated
Chemodynamic therapy (CDT) dependent on the conversion of endogenous hydrogen …

Quinones are plant-derived secondary metabolites that present some anti-proliferation and
anti-metastasis effects in various cancer types both in vitro and in vivo. This review focuses …