Methods A PubMed search was conducted using the search terms “graft versus host
disease,”“acute GVHD,”“chronic GVHD,”“pathophysiology,”“diagnosis,” and “treatment.” …

Skin fibrosis is a physiopathological process featuring the excessive deposition of
extracellular matrix (ECM), which is the main architecture that provides structural support …

Systemic sclerosis (scleroderma, SSc) is an incurable autoimmune disease with high
morbidity and mortality rates. Here, we conducted a population-scale single-cell genomic …

Several international recommendations address the assessment of graft-versus-host
disease (GvHD) after hematopoietic cell transplantation (HCT). This position statement by …

Graft-versus-host disease is a common complication following allogeneic hematopoetic
stem cell transplantation that can affect multiple organ systems, including the eyes. Ocular …

Haematological malignancies induce important alterations of the immune system, which
account for the high frequency of autoimmune complications observed in patients …

Chronic GVHD (cGVHD) is the most relevant cause of late non-relapse morbidity and
subsequent mortality (approximately 25%) following allo-HSCT (Grube et al. 2016). Its …

Allogeneic hematopoietic stem cell transplantation (allo‐HCT) is an effective therapy for the
treatment of high‐risk haematological malignant disorders and other life‐threatening …

The skin is the outermost mechanical barrier where dynamic immune reactions take place
and is the most commonly affected site in both acute and chronic graft-versus-host disease …

The composition of the gut microbiome influences the clinical course after allogeneic
hematopoietic stem cell transplantation (HSCT), but little is known about the relevance of …