Mobile genetic elements associated with antimicrobial resistance
SR Partridge, SM Kwong, N Firth… - Clinical microbiology …, 2018 - Am Soc Microbiol
Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …
increasing major health care problem around the world. It is now abundantly clear that both …
Mobile oxazolidinone resistance genes in Gram-positive and Gram-negative bacteria
S Schwarz, W Zhang, XD Du, H Krüger… - Clinical microbiology …, 2021 - Am Soc Microbiol
Seven mobile oxazolidinone resistance genes, including cfr, cfr (B), cfr (C), cfr (D), cfr (E),
optrA, and poxtA, have been identified to date. The cfr genes code for 23S rRNA methylases …
optrA, and poxtA, have been identified to date. The cfr genes code for 23S rRNA methylases …
Detection of mobile genetic elements associated with antibiotic resistance in Salmonella enterica using a newly developed web tool: MobileElementFinder
MHK Johansson, V Bortolaia… - Journal of …, 2021 - academic.oup.com
Objectives Antimicrobial resistance (AMR) in clinically relevant bacteria is a growing threat
to public health globally. In these bacteria, antimicrobial resistance genes are often …
to public health globally. In these bacteria, antimicrobial resistance genes are often …
Conjugative plasmids interact with insertion sequences to shape the horizontal transfer of antimicrobial resistance genes
It is well established that plasmids play an important role in the dissemination of
antimicrobial resistance (AMR) genes; however, little is known about the role of the …
antimicrobial resistance (AMR) genes; however, little is known about the role of the …
Emergence of a plasmid-encoded resistance-nodulation-division efflux pump conferring resistance to multiple drugs, including tigecycline, in Klebsiella pneumoniae
L Lv, M Wan, C Wang, X Gao, Q Yang, SR Partridge… - MBio, 2020 - Am Soc Microbiol
Transporters belonging to the chromosomally encoded resistance-nodulation-division
(RND) superfamily mediate multidrug resistance in Gram-negative bacteria. However, the …
(RND) superfamily mediate multidrug resistance in Gram-negative bacteria. However, the …
Evolutionary pathways and trajectories in antibiotic resistance
Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …
provided a wealth of information, but knowledge regarding “what happened” has precluded …
[HTML][HTML] Role of mobile genetic elements in the global dissemination of the carbapenem resistance gene blaNDM
The mobile resistance gene bla NDM encodes the NDM enzyme which hydrolyses
carbapenems, a class of antibiotics used to treat some of the most severe bacterial …
carbapenems, a class of antibiotics used to treat some of the most severe bacterial …
[HTML][HTML] A role for ColV plasmids in the evolution of pathogenic Escherichia coli ST58
CJ Reid, ML Cummins, S Börjesson… - Nature …, 2022 - nature.com
Escherichia coli ST58 has recently emerged as a globally disseminated uropathogen that
often progresses to sepsis. Unlike most pandemic extra-intestinal pathogenic E. coli …
often progresses to sepsis. Unlike most pandemic extra-intestinal pathogenic E. coli …
Transposons: the agents of antibiotic resistance in bacteria
S Babakhani, M Oloomi - Journal of basic microbiology, 2018 - Wiley Online Library
Transposons are a group of mobile genetic elements that are defined as a DNA sequence.
Transposons can jump into different places of the genome; for this reason, they are called …
Transposons can jump into different places of the genome; for this reason, they are called …
Survival and evolution of a large multidrug resistance plasmid in new clinical bacterial hosts
A Porse, K Schønning, C Munck… - Molecular biology and …, 2016 - academic.oup.com
Large conjugative plasmids are important drivers of bacterial evolution and contribute
significantly to the dissemination of antibiotic resistance. Although plasmid borne multidrug …
significantly to the dissemination of antibiotic resistance. Although plasmid borne multidrug …