Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …

Seven mobile oxazolidinone resistance genes, including cfr, cfr (B), cfr (C), cfr (D), cfr (E),
optrA, and poxtA, have been identified to date. The cfr genes code for 23S rRNA methylases …

Objectives Antimicrobial resistance (AMR) in clinically relevant bacteria is a growing threat
to public health globally. In these bacteria, antimicrobial resistance genes are often …

It is well established that plasmids play an important role in the dissemination of
antimicrobial resistance (AMR) genes; however, little is known about the role of the …

Transporters belonging to the chromosomally encoded resistance-nodulation-division
(RND) superfamily mediate multidrug resistance in Gram-negative bacteria. However, the …

Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …

The mobile resistance gene bla NDM encodes the NDM enzyme which hydrolyses
carbapenems, a class of antibiotics used to treat some of the most severe bacterial …

Escherichia coli ST58 has recently emerged as a globally disseminated uropathogen that
often progresses to sepsis. Unlike most pandemic extra-intestinal pathogenic E. coli …

Transposons are a group of mobile genetic elements that are defined as a DNA sequence.
Transposons can jump into different places of the genome; for this reason, they are called …

Large conjugative plasmids are important drivers of bacterial evolution and contribute
significantly to the dissemination of antibiotic resistance. Although plasmid borne multidrug …