Background The brain was once thought of as an insulin-insensitive organ. We now know
that the insulin receptor is present throughout the brain and serves important functions in …

The latest studies have indicated a strong relationship between systemic insulin resistance
(IR) and higher incidence of neurodegeneration, dementia, and mild cognitive impairment …

Ischemic stroke is a devastating disease with long-term disability. However, the
pathogenesis is unclear and treatments are limited. Meisoindigo, a second-generation …

The multifactorial nature of Alzheimer's disease (AD) is a reason for the lack of effective
drugs as well as a basis for the development of “multi-target-directed ligands”(MTDLs). As …

Common environmental pollutants and drugs encountered in everyday life can cause toxic
damage to the body through oxidative stress, inflammatory stimulation, induction of …

The ART program in low-and middle-income countries (LMIC) like India, follows a public
health approach with a standardized regimen for all people living with HIV (PLHIV). Based …

Although myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) has a specific and
distinctive profile of clinical features, the disease remains an enigma because causal …

Scope In this study, it has been investigated whether the neuroprotective efficacy of
epigallocatechin‐3‐gallate (EGCG) is mediated by inhibition of canonical and noncanonical …

With the rapid development of electronic information in the past 30 years, technical
achievements based on electromagnetism have been widely used in various fields …

Fluorides occur naturally in the environment, the daily exposure of human organism to
fluorine mainly depends on the intake of this element with drinking water and it is connected …