Involvement of Opioid System and TRPM8/TRPA1 Channels in the Antinociceptive Effect of Spirulina platensis
MA Freitas, A Vasconcelos, ECD Gonçalves… - Biomolecules, 2021 - mdpi.com
Spirulina platensis is a “super-food” and has attracted researchers' attention due to its anti-
inflammatory, antioxidant, and analgesic properties. Herein, we investigated the …
inflammatory, antioxidant, and analgesic properties. Herein, we investigated the …
Baicalin prevents the up‐regulation of TRPV1 in dorsal root ganglion and attenuates chronic neuropathic pain
Z Wang, D Ling, C Wu, J Han… - Veterinary Medicine and …, 2020 - Wiley Online Library
Background Neuropathic pain is a major public health problem because it has a
considerable impact on life quality of patients. TRP channels from dorsal root ganglion …
considerable impact on life quality of patients. TRP channels from dorsal root ganglion …
Puerarin ameliorates allodynia and hyperalgesia in rats with peripheral nerve injury
HT Xie, ZY Xia, X Pan, B Zhao… - Neural Regeneration …, 2018 - journals.lww.com
Puerarin is a major active ingredient of the traditional Chinese plant medicine, Radix
Puerariae, and commonly used in the treatment of myocardial and cerebral ischemia …
Puerariae, and commonly used in the treatment of myocardial and cerebral ischemia …
TRPV1 is involved in the antinociceptive effects of resveratrol in paclitaxel-induced neuropathic pain
Y Zhang, F Huang, Y Xu, W Xiang, C Xie - All Life, 2021 - Taylor & Francis
Paclitaxel-induced peripheral neuropathic pain (PIPNP) is a major therapy-and dose-limiting
side effect that is extremely laborious to treat. Resveratrol (Res), with a structure name of 3 …
side effect that is extremely laborious to treat. Resveratrol (Res), with a structure name of 3 …
Oral treatment with Berberine reduces peripheral nociception: Possible interaction with different nociceptive pathways activated by different allogeneic substances
MP Del Gaudio, SI Kraus, TM Melzer, PS Bustos… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Berberine was identified in extracts of Berberis ruscifolia
Lam., a plant used in traditional medicine as an analgesic. Its presence may be involved in …
Lam., a plant used in traditional medicine as an analgesic. Its presence may be involved in …
Beneficial effect of mirtazapine on diabetes-induced hyperalgesia: involvement of TRPV1 and ASIC1 channels in the spinal cord and dorsal root ganglion
Objectives: Neuropathic pain reduces the life qualities of patients with Diabetes mellitus.
Clinical guidelines recommend relief in diabetic neuropathic pain through the use of some …
Clinical guidelines recommend relief in diabetic neuropathic pain through the use of some …
Effects of simvastatin beyond dyslipidemia: Exploring its antinociceptive action in an animal model of complex regional pain syndrome-type I
G Vieira, J Cavalli, ECD Gonçalves… - Frontiers in …, 2017 - frontiersin.org
Simvastatin is a lipid-lowering agent that blocks the production of cholesterol through
inhibition of 3-hydroxy-methyl-glutaryl coenzyme A (HMG-CoA) reductase. In addition …
inhibition of 3-hydroxy-methyl-glutaryl coenzyme A (HMG-CoA) reductase. In addition …
[HTML][HTML] Antinociceptive effects of new pyrazoles compounds mediated by the ASIC-1α channel, TRPV-1 and μMOR receptors
IF Florentino, DPB Silva, CS Cardoso… - Biomedicine & …, 2019 - Elsevier
Pyrazoles are potent medicinal scaffolds and exhibit a wide spectrum of biological activities,
such as analgesic, anti-inflammatory and antipyretic. In this paper we report on research we …
such as analgesic, anti-inflammatory and antipyretic. In this paper we report on research we …
Evaluation of the systemic and spinal antinociceptive effect of a new hybrid NSAID tetrahydropyran derivative
GM Gonçalves, JM Oliveira… - Clinical and …, 2022 - Wiley Online Library
Pain is responsible for inducing physical and mental stress, interfering negatively in patients'
quality of life. Classic analgesic drugs, such as opioids and non‐steroidal anti‐inflammatory …
quality of life. Classic analgesic drugs, such as opioids and non‐steroidal anti‐inflammatory …
Root bark of Discaria americana attenuates pain: A pharmacological evidence of interaction with opioidergic system and TRP/ASIC channels
Abstract Ethnopharmacological relevance Discaria americana (Rhamnaceae) root bark
infusion have been used in traditional medicine as antipyretic, tonic, ameliorative of stomach …
infusion have been used in traditional medicine as antipyretic, tonic, ameliorative of stomach …