Cardiovascular diseases (CVDs) are the leading cause of premature death and disability in
humans and their incidence is on the rise globally. Given their substantial contribution …

Statins are a family of drugs that are used for treating hyperlipidaemia with a recognized
capacity to prevent cardiovascular disease events. They inhibit β‐hydroxy β‐methylglutaryl …

Abstract The Canadian Consensus Working Group has updated its evaluation of the
literature pertaining to statin intolerance and adverse effects. This overview introduces a …

Epidemiologic studies have, variably, shown the concomitant use of statin drugs to be
beneficial to cancer outcomes. Statin drugs have been FDA approved for three decades for …

All over the world, metabolic syndrome constitutes severe health problems. Multiple factors
have been reported in the pathogenesis of metabolic syndrome. Metabolic disorders result …

Hyperlipidemia, the most common form of dyslipidemia, is the main source of cardiovascular
disorders, characterized by elevated level of total cholesterol (TC), triglycerides (TG) and low …

Objectives The myoblast cell line, C2C12, has been utilised extensively in vitro as an
examination model in understanding metabolic disease progression. Although it is …

Hepatic adverse effects are one of the most commonly known adverse effects reported with
statins. Frequently, fear of serious hepatic effects contributes to underutilization of statins as …

Decreases in global cardiovascular disease (CVD) mortality and morbidity in recent
decades can be partly attributed to cholesterol reduction through statin use. n-3 long chain …

Achondroplasia (ACH), the most common form of human dwarfism, is caused by an
activating autosomal dominant mutation in the fibroblast growth factor receptor-3 gene …