Establishing outcome measures in early knee osteoarthritis

CA Emery, JL Whittaker, A Mahmoudian… - Nature Reviews …, 2019 - nature.com
The classification and monitoring of individuals with early knee osteoarthritis (OA) are
important considerations for the design and evaluation of therapeutic interventions and …

A JAK inhibitor for treatment of rheumatoid arthritis: the baricitinib experience

PC Taylor, C Laedermann, R Alten, E Feist… - Journal of Clinical …, 2023 - mdpi.com
Baricitinib, an oral selective Janus kinase (JAK) 1/JAK2 inhibitor, is approved as
monotherapy or in combination with methotrexate for treating adults with moderate-to-severe …

Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior …

R Westhovens, WFC Rigby, D van der Heijde… - Annals of the …, 2021 - ard.bmj.com
Objectives To investigate efficacy and safety of the Janus kinase-1 inhibitor filgotinib in
patients with active rheumatoid arthritis (RA) with limited or no prior methotrexate (MTX) …

Effectiveness of methotrexate with step-down glucocorticoid remission induction (COBRA Slim) versus other intensive treatment strategies for early rheumatoid arthritis …

P Verschueren, D De Cock, L Corluy, R Joos… - Annals of the …, 2017 - ard.bmj.com
Objectives Combining disease-modifying antirheumatic drugs (DMARDs) with
glucocorticoids (GCs) is an effective treatment strategy for early rheumatoid arthritis (ERA) …

Patient-relevant outcomes: what are we talking about? A scoping review to improve conceptual clarity

C Kersting, M Kneer, A Barzel - BMC health services research, 2020 - Springer
Background With respect to patient-centered care, measuring care effects based on patient-
relevant outcomes is becoming increasingly important. There is some uncertainty about …

Effectiveness of different combinations of DMARDs and glucocorticoid bridging in early rheumatoid arthritis: two-year results of CareRA

V Stouten, R Westhovens, S Pazmino… - …, 2019 - academic.oup.com
Objectives To investigate whether MTX should be combined with an additional DMARD and
bridging glucocorticoids as initial treatment for patients with early RA to induce an effective …

Psychosocial burden predicts sustained remission in early rheumatoid arthritis: unraveling the complex interplay of well‐being and disease activity

M Doumen, D De Cock, S Pazmino… - Arthritis care & …, 2023 - Wiley Online Library
Objective This study investigated how psychosocial aspects of disease affect the probability
of achieving sustained remission in early rheumatoid arthritis (RA) and explored the …

Achieving pain control in early rheumatoid arthritis with baricitinib monotherapy or in combination with methotrexate versus methotrexate monotherapy

PC Taylor, R Alten, JMÁ Gracia, Y Kaneko, C Walls… - RMD open, 2022 - rmdopen.bmj.com
Objectives This post hoc analysis assessed speed, magnitude and maintenance of pain
improvement in patients with early rheumatoid arthritis (RA) receiving baricitinib, baricitinib …

Psychological stress in rheumatoid arthritis: a systematic scoping review

D De Cock, M Doumen, C Vervloesem… - Seminars in Arthritis and …, 2022 - Elsevier
Background Rheumatoid arthritis (RA) considerably impacts patients' mental health.
However, it is largely unclear how people suffering from RA experience psychological stress …

Longitudinal trajectories of fatigue in early RA: the role of inflammation, perceived disease impact and early treatment response

M Doumen, S Pazmino, D Bertrand… - Annals of the …, 2022 - ard.bmj.com
Objective Fatigue is common in rheumatoid arthritis (RA). We aimed to explore its
longitudinal course, predictors and association with disease activity in early RA. Methods …