In silico study to identify novel NEK7 inhibitors from natural sources by a combination strategy

H Zhang, C Lu, Q Yao, Q Jiao - Molecular Diversity, 2024 - Springer
Cancer poses a significant global health challenge and significantly contributes to mortality.
NEK7, related to the NIMA protein kinase family, plays a crucial role in spindle assembly and …

[HTML][HTML] Anti-aging effects of polysaccharides from quinoa (Chenopodium quinoa Willd.) in improving memory and cognitive function

Y Hu, J Zhou, Y Cao, J Zhang, L Zou - Journal of Functional Foods, 2022 - Elsevier
Given that the polysaccharide of Quinoa (Chenopodium quinoa Willd., QP) exhibited
preliminarily antioxidant activity in our previous studies, herein its anti-aging activities being …

Profiling of Petroselinum sativum (mill.) fuss phytoconstituents and assessment of their biocompatibility, antioxidant, anti-aging, wound healing, and antibacterial …

I Mahdi, P Imbimbo, H Annaz, WB Bakrim… - Frontiers in …, 2024 - frontiersin.org
Petroselinum sativum, known as parsley, is a fragrant herb that possesses a rich heritage of
utilization in traditional medicinal practices. In this study, we annotated the phytocontents of …

Efficient enzymatic synthesis of lipophilic phenolic glycoside azelaic acid esters and their depigmenting activity

H Xu, X Li, X Xin, L Mo, Y Zou… - Journal of Agricultural and …, 2021 - ACS Publications
In this paper, an enzymatic route for synthesizing phenolic glycoside azelaic acid esters was
successfully set up via lipase-catalyzed esterification and transesterification. Among the …

Hesperetin attenuates UVA‐induced photodamage in human dermal fibroblast cells

Z Lu, Q Xia, Y Cheng, Q Lu, Y Li, N Zeng… - Journal of Cosmetic …, 2022 - Wiley Online Library
Abstract Background Ultraviolet A (UVA) radiation causes skin damage. Recently, natural
compounds have become an interest to protect skin from UV‐induced photodamages …

Dietary polyphenol oleuropein and its metabolite hydroxytyrosol are moderate skin permeable elastase and collagenase inhibitors with synergistic cellular antioxidant …

H Li, H He, C Liu, T Akanji, J Gutkowski… - … Journal of Food …, 2022 - Taylor & Francis
Oleuropein (OLE) and hydroxytyrosol (HT) are dietary polyphenols with skin beneficial
effects but their effects on skin-ageing-related enzymes are not clear. Herein, we evaluated …

Cryptomphalus aspersa Egg Extract Protects against Human Stem Cell Stress-Induced Premature Senescence

Z Outskouni, C Christodoulou, A Goutas… - International Journal of …, 2024 - mdpi.com
Cellular senescence is a tightly regulated pathophysiologic process and is caused by
replicative exhaustion or external stressors. Since naturally derived bioactive compounds …

Biological Activities of Lamiaceae Species: Bio-Guided Isolation of Active Metabolites from Salvia officinalis L.

E Tsitsigianni, EM Tomou, C Almpani, MC Rallis… - Agronomy, 2023 - mdpi.com
Lamiaceae family includes various medicinal and aromatic plants used in cosmetics and
pharmaceutical industries. The present study aimed to investigate in vitro the cytotoxic …

Ionic liquid microcapsules for the topical delivery of pterostilbene: Enhanced transdermal delivery and anti-wrinkle and skin brightening effects

D Bai, H Chen, L Liu, N Xiang, J Zhang, C Wu… - Journal of Molecular …, 2024 - Elsevier
Pterostilbene (PTB) is a hydrophobic compound derived from plants in the Astragalus family.
PTB possesses remarkable skin brightening and antioxidant properties. However, delivery …

Health-Promoting Properties of Natural Flavonol Glycosides Isolated from Staphylea pinnata L.

I Paolillo, G Roscigno, M Innangi, JG Zorrilla… - International Journal of …, 2024 - mdpi.com
Staphylea, also called bladdernuts, is a genus of plants belonging to the family
Staphyleaceae, widespread in tropical or temperate climates of America, Europe, and the …