The sensory epithelium of the mammalian inner ear contains two types of mechanosensory
cells: inner (IHC) and outer hair cells (OHC). They both transduce mechanical force …

Sound is encoded at synapses between cochlear inner hair cells and the auditory nerve.
These synapses are anatomically and functionally specialized to transmit acoustic …

Ribbon synapses of cochlear inner hair cells (IHCs) undergo molecular assembly and
extensive functional and structural maturation before hearing onset. Here, we characterized …

Hair cell ribbon synapses exhibit several distinguishing features. Structurally, a dense body,
or ribbon, is anchored to the presynaptic membrane and tethers synaptic vesicles; …

We studied the role of the synaptic ribbon for sound encoding at the synapses between
inner hair cells (IHCs) and spiral ganglion neurons (SGNs) in mice lacking RIBEYE …

Synaptic ribbons are large proteinaceous scaffolds at the active zone of ribbon synapses
that are specialized for rapid sustained synaptic vesicles exocytosis. A single ribbon‐specific …

Physical activity plays an important role in preventing chronic disease in adults and the
elderly. Exercise has beneficial effects on the nervous system, including at the …

Inner hair cells (IHCs) of the cochlea use ribbon synapses to transmit auditory information
faithfully to spiral ganglion neurons (SGNs). In the present study, we used genetic disruption …

Objective. Intracortical brain interfaces are an ever evolving technology with growing
potential for clinical and research applications. The chronic tissue response to these devices …

In the mammalian cochlea, sound is encoded at synapses between inner hair cells (IHCs)
and type I spiral ganglion neurons (SGNs). Each SGN receives input from a single IHC …