Role of cannabidiol in the therapeutic intervention for substance use disorders

F Navarrete, MS García-Gutiérrez… - Frontiers in …, 2021 - frontiersin.org
Drug treatments available for the management of substance use disorders (SUD) present
multiple limitations in efficacy, lack of approved treatments or alarming relapse rates. These …

Cannabidiol and substance use disorder: Dream or reality

S Karimi-Haghighi, Y Razavi, D Iezzi, AF Scheyer… - …, 2022 - Elsevier
Background Cannabidiol (CBD) is one of the major constituents of Cannabis sativa L. that
lacks psychotomimetic and rewarding properties and inhibits the rewarding and reinforcing …

Cannabidiol in the context of substance use disorder treatment: A systematic review

V Paulus, J Billieux, A Benyamina, L Karila - Addictive behaviors, 2022 - Elsevier
Introduction Cannabidiol (CBD) is a phytocannabinoid found in the Cannabis plant. CBD
has received significant medical attention in relation to its anticonvulsant, anxiolytic, and …

Cannabidiol Analogue CIAC001 for the Treatment of Morphine-Induced Addiction by Targeting PKM2

S Jin, C Lin, Y Wang, H Wang, X Wen… - Journal of Medicinal …, 2023 - ACS Publications
Opioid addiction is a chronically relapsing disorder that causes critical public health
problems. Currently, there is a lack of effective drug treatment. Herein, one cannabidiol …

Medial prefrontal cortex mechanisms of cannabidiol-induced aversive memory reconsolidation impairments

H Bayer, CAJ Stern, F Troyner, L Gazarini… - …, 2022 - Elsevier
Growing evidence indicates that cannabidiol (CBD), a substance present in the Cannabis
sativa plant, has potential therapeutic value to regulate abnormal emotional memories …

Cannabidiol efficiently suppressed the acquisition and expression of methamphetamine-induced conditioned place preference in the rat

M Anooshe, K Nouri, S Karimi-Haghighi… - Behavioural Brain …, 2021 - Elsevier
Methamphetamine (MET) is one of the most prevalently abused psychostimulants in the
world with drastic repercussions. Several studies emphasized the inhibitory effect of …

Cannabidiol (CBD) treatment improves spatial memory in 14-month-old female TAU58/2 transgenic mice

F Kreilaus, M Przybyla, L Ittner, T Karl - Behavioural Brain Research, 2022 - Elsevier
Frontotemporal dementia (FTD) and Alzheimer's disease (AD) share the pathological
hallmark of intracellular neurofibrillary tangles, which result from the hyperphosphorylation …

[HTML][HTML] Cannabidiol prevents several of the behavioral alterations related to cocaine addiction in mice

JC Ledesma, C Manzanedo, MA Aguilar - Progress in Neuro …, 2021 - Elsevier
Cocaine dependence is a highly prevalent disease in modern society and lacks an effective
treatment. Cannabidiol (CBD), a major non-psychoactive constituent of Cannabis sativa, has …

Cannabidiol impairs the rewarding effects of methamphetamine: Involvement of dopaminergic receptors in the nucleus accumbens

A Sharifi, S Karimi-Haghighi, R Shabani… - Progress in Neuro …, 2022 - Elsevier
Cannabidiol, as component of cannabis, can potentially hinder the rewarding impact of drug
abuse; however, its mechanism is ambiguous. Moreover, the nucleus accumbens (NAc), as …

Use of cannabidiol (CBD) for the treatment of cognitive impairment in psychiatric and neurological illness: A narrative review.

R Ortiz, S Rueda, P Di Ciano - Experimental and Clinical …, 2023 - psycnet.apa.org
Cannabidiol (CBD) is one of the major phytocannabinoids present in the cannabis plant,
with no acute psychotropic effects and a favorable safety and abuse liability profile. Animal …