Methods These are the consensus statements and guideline of ASHP, IDSA, the Pediatric
Infectious Diseases Society (PIDS), and SIDP. Guideline panel composition consisted of …

Despite the wide clinical use of vancomycin, controversy remains regarding its optimal
dosage regimens. This can be attributed to the large between-and within-subject variability …

Antimicrobial resistance is a major global health challenge. As few new efficacious
antibiotics will become available in the near future, peptide antibiotics continue to be major …

Background Clinical practice guidelines or recommendations often require timely and
regular updating as new evidence emerges, because this can alter the risk-benefit trade-off …

Study Objective The optimal pharmacodynamic parameter for the prediction of efficacy of
vancomycin is the area under the concentration–time curve (AUC), and current published …

Purpose The purpose of this study was to (1) determine whether academic medical centers
implemented area under the concentration–time curve (AUC)–based monitoring for …

Aims Vancomycin is an important antibiotic for critically ill patients with Gram‐positive
bacterial infections. Critically ill patients typically have severely altered pathophysiology …

Background Vancomycin is a first-line antibiotic for methicillin-resistant Staphylococcus
aureus infections or other Gram-positive infections. The area under the curve (AUC) to …

Background There are conflicts in guideline recommendations about the value and range of
vancomycin trough concentration during therapeutic drug monitoring (TDM). This …

Background Current guidelines for intravenous vancomycin identify drug exposure (as
indicated by the AUC) as the best pharmacokinetic (PK) indicator of therapeutic outcome …