Preparation and evaluation of nystatin-loaded solid-lipid-nanoparticles for topical delivery

LH Samein - Asian Journal of Pharmaceutical Research, 2014 - indianjournals.com
The purpose of present study was to prepare SLN incorporating an antifungal drug such as
Nystatin and study its effect on skin localization of drug when administered through a …

Polymeric and lipid-based materials for topical nanoparticle delivery systems

KR Pawar, RJ Babu - Critical reviews™ in therapeutic drug …, 2010 - dl.begellhouse.com
The delivery of drugs and cosmetic actives to the skin by nanoparticle formulations has a
number of advantages over conventional formulations. Nanoparticle formulations offer …

Enhanced topical econazole antifungal efficacy by amine-functionalized silica nanoparticles

M Montazeri, M Razzaghi-Abyaneh… - Bulletin of Materials …, 2020 - Springer
The present study aims at developing efficient econazole (ECO) platforms as topical creams
for the treatment of fungal skin infections. The hexagonal mesoporous silica nanoparticle …

Development of thermodynamically stable nanostructured lipid carrier system using central composite design for zero order permeation of econazole nitrate through …

L Keshri, K Pathak - Pharmaceutical development and technology, 2013 - Taylor & Francis
The investigation was aimed at developing thermodynamically stable topical delivery system
of nanostructured lipid carrier of econazole nitrate (EN) for the treatment of deep seated …

Insightful exploring of advanced nanocarriers for the topical/transdermal treatment of skin diseases

GM El-Zaafarany, M Nasr - Pharmaceutical development and …, 2021 - Taylor & Francis
Dermatological products constitute a big segment of the pharmaceutical market. From
conventional products to more advanced ones, a wide variety of dosage forms have been …

[PDF][PDF] Application of central composite design for development and optimization of eflornithine hydrochloride-loaded sustained release solid lipid microparticles

IK Grewal, S Singh, S Arora… - Biointerface Res. Appl …, 2021 - biointerfaceresearch.com
Topical application of eflornithine hydrochloride (EFH) is the only available non-hormonal
and non-systemic choice available for hirsutism treatment. EFH has low permeability (log P …

Lipid nanoparticles for dermal drug delivery

PG Kakadia, BR Conway - Current pharmaceutical design, 2015 - ingentaconnect.com
Lipid based drug delivery systems have been widely studied and reported over the past
decade and offer a useful alternative to other colloidal drug delivery systems. Skin is a …

Lipid nanoparticles production by supercritical fluid assisted emulsion–diffusion

R Campardelli, M Cherain, C Perfetti, C Iorio… - The Journal of …, 2013 - Elsevier
In this work a supercritical technology is proposed to improve the classical
emulsification/diffusion technology for lipid nanoparticles (LNs) production. The process is …

[HTML][HTML] Optimization of a cefuroxime axetil-loaded liquid self-nanoemulsifying drug delivery system: enhanced solubility, dissolution and caco-2 cell uptake

AA Khan, A Atiya, S Akhtar, Y Yadav, KA Qureshi… - Pharmaceutics, 2022 - mdpi.com
Cefuroxime axetil (CA) is an oral cephalosporin which hydrolyzes rapidly to the active parent
compound cefuroxime. CA is known to have incomplete oral bioavailability (30–50%) due to …

SLN-and NLC-encapsulating antifungal agents: skin drug delivery and their unexplored potential for treating onychomycosis

T Gratieri, AP Krawczyk-Santos… - Current …, 2017 - ingentaconnect.com
Background: Lipid nanoparticles have been extensively studied for drug delivery of
antifungal drugs, especially for dermatophytosis treatments. They can accumulate in skin …