Human papillomavirus as a driver of head and neck cancers

ME Sabatini, S Chiocca - British journal of cancer, 2020 - nature.com
The human papillomavirus (HPV) family includes more than 170 different types of virus that
infect stratified epithelium. High-risk HPV is well established as the primary cause of cervical …

[PDF][PDF] Review of HPV-related diseases and cancers

P Brianti, E De Flammineis, SR Mercuri - New Microbiol, 2017 - newmicrobiologica.org
Human papillomavirus (HPV) is a double-stranded circular DNA virus belonging to the
papillomavirus family. It is transmitted by skin-to-skin or mucosa-to-mucosa contact and …

[HTML][HTML] Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments

HU Bernard, RD Burk, Z Chen, K Van Doorslaer… - Virology, 2010 - Elsevier
We present an expansion of the classification of the family Papillomaviridae, which now
contains 29 genera formed by 189 papillomavirus (PV) types isolated from humans (120 …

[HTML][HTML] Human papillomavirus genome variants

RD Burk, A Harari, Z Chen - Virology, 2013 - Elsevier
Amongst the human papillomaviruses (HPVs), the genus Alphapapillomavirus contains HPV
types that are uniquely pathogenic. They can be classified into species and types based on …

Human papillomaviruses as infectious agents in gynecological cancers. oncogenic properties of viral proteins

DA Haręża, JR Wilczyński, E Paradowska - International journal of …, 2022 - mdpi.com
Human papillomaviruses (HPVs), which belong to the Papillomaviridae family, constitute a
group of small nonenveloped double-stranded DNA viruses. HPV has a small genome that …

[HTML][HTML] Role of human papillomaviruses in carcinogenesis

R Ghittoni, R Accardi, S Chiocca… - …, 2015 - ncbi.nlm.nih.gov
The human papillomavirus (HPV) family comprises more than 170 different types that
preferentially infect the mucosa of the genitals, upper-respiratory tract, or the skin. The 'high …

Understanding and learning from the success of prophylactic human papillomavirus vaccines

JT Schiller, DR Lowy - Nature Reviews Microbiology, 2012 - nature.com
An estimated 5% of human cancers are caused by human papillomavirus (HPV) infections,
and most of these cancers are of the cervix. Two prophylactic HPV vaccines that target the …

Using time-structured data to estimate evolutionary rates of double-stranded DNA viruses

C Firth, A Kitchen, B Shapiro… - Molecular biology …, 2010 - academic.oup.com
Double-stranded (ds) DNA viruses are often described as evolving through long-term
codivergent associations with their hosts, a pattern that is expected to be associated with low …

HPV16 sublineage associations with histology-specific cancer risk using HPV whole-genome sequences in 3200 women

L Mirabello, M Yeager, M Cullen… - JNCI: Journal of the …, 2016 - academic.oup.com
Background: HPV16 is a common sexually transmitted infection although few infections lead
to cervical precancer/cancer; we cannot distinguish nor mechanistically explain why only …

HPV sequencing facilitates ultrasensitive detection of HPV circulating tumor DNA

E Leung, K Han, J Zou, Z Zhao, Y Zheng, TT Wang… - Clinical Cancer …, 2021 - AACR
Abstract Purpose: Human papillomavirus (HPV) DNA offers a convenient circulating tumor
DNA (ctDNA) marker for HPV-associated malignancies, but current methods, such as digital …