Distal Onco-sphere: Cluster Metastasis

PE Saw, E Song - Tumor Ecosystem: An Ecological View of Cancer …, 2023 - Springer
In order for cancer cells to metastasize, they need to be disseminated from the local onco-
sphere. During this process, cancer cells are known as circulating tumor cells (CTCs) which …

The portrayal of macrophages as tools and targets: a paradigm shift in cancer management

N Jain, DA Srinivasarao, P Famta, S Shah… - Life Sciences, 2023 - Elsevier
Macrophages play a major role in maintaining an organism's physiology, such as
development, homeostasis, tissue repair, and immunity. These immune cells are known to …

Cell Fusion and Syncytia Formation in Cancer

M Sieler, T Dittmar - Syncytia: Origin, Structure, and Functions, 2023 - Springer
The natural phenomenon of cell–cell fusion does not only take place in physiological
processes, such as placentation, myogenesis, or osteoclastogenesis, but also in …

Gravity-based microfiltration reveals unexpected prevalence of circulating tumor cell clusters in ovarian and colorectal cancer

A Meunier, JA Hernández-Castro, N Chahley… - BioRxiv, 2019 - biorxiv.org
Circulating tumor cells (CTCs) are rare (few cells per milliliter of blood) and mostly isolated
as single cell CTCs (scCTCs). CTC clusters (cCTCs), even rarer, are of growing interest …

Alanine serine cysteine transporter 2

M Sieler, T Dittmar - Syncytia: Origin, Structure, and Functions, 2023 - books.google.com
Cell fusion is a biological mechanism crucial for physiological processes, such as
fertilization and placentation, wound healing, and tissue regeneration as well as …

[HTML][HTML] Прогностическая значимость атипичных/гибридных форм клеток EpCAM+ CD45+ в крови у больных раком эндометрия

ЕВ Кайгородова, ИС Заваруев… - Опухоли женской …, 2023 - cyberleninka.ru
Введение. Рак эндометрия (РЭ) занимает лидирующие позиции в структуре
онкогинекологической патологии. По данным современной литературы, в процессах …

Cell-in-cell structures in gastrointestinal tumors: biological relevance and clinical applications

I Druzhkova, N Ignatova, M Shirmanova - Journal of Personalized …, 2023 - mdpi.com
This review summarizes information about cell-in-cell (CIC) structures with a focus on
gastrointestinal tumors. The phenomenon when one cell lives in another one has attracted …

A novel computational approach to identify cancer cells in scRNA-seq data

W Gasper, F Rossi, M Ligorio, D Ghersi - bioRxiv, 2022 - biorxiv.org
Single-cell RNA-seq is an invaluable research tool that allows for the investigation of gene
expression in heterogeneous cancer cell populations in ways that bulk RNA-seq cannot …

ГИБРИДНЫЕ/АТИПИЧНЫЕ ФОРМЫ ЦИРКУЛИРУЮЩИХ ОПУХОЛЕВЫХ КЛЕТОК: СОВРЕМЕННОЕ СОСТОЯНИЕ ПРОБЛЕМЫ

ЕВ Кайгородова, АВ Козик, ИС Заваруев… - Биохимия, 2022 - elibrary.ru
Одним из наиболее распространённых заболеваний во всём мире является рак,
лечение которого сопряжено со многими проблемами, такими как лекарственная и …

Re-aligning patient prognosis: the role of collagen in establishing an immunosuppressive microenvironment and facilitating cancer cell dissemination in pancreatic …

MK Callaway - 2021 - search.proquest.com
Pancreatic ductal adenocarcinoma (PDA) is an aggressive cancer with particularly poor
clinical outcomes, in part, because of a dramatically altered stromal environment and striking …