[HTML][HTML] Male infertility and oxidative stress: a focus on the underlying mechanisms

RJ Aitken, JR Drevet, A Moazamian, P Gharagozloo - Antioxidants, 2022 - mdpi.com
Reactive oxygen species (ROS) play a critical role in defining the functional competence of
human spermatozoa. When generated in moderate amounts, ROS promote sperm …

Reactive oxygen species as mediators of sperm capacitation and pathological damage

RJ Aitken - Molecular reproduction and development, 2017 - Wiley Online Library
Oxidative stress plays a major role in the life and death of mammalian spermatozoa. These
gametes are professional generators of reactive oxygen species (ROS), which appear to …

[HTML][HTML] Impact of oxidative stress on male and female germ cells: implications for fertility

RJ Aitken - Reproduction, 2020 - rep.bioscientifica.com
Male and female germ lines are vulnerable to oxidative stress. In spermatozoa, such stress
triggers a lipid peroxidation cascade that culminates in the generation of electrophilic lipid …

Effect of oxidative stress on male reproduction

A Agarwal, G Virk, C Ong… - The world journal of …, 2014 - synapse.koreamed.org
Infertility affects approximately 15% of couples trying to conceive, and a male factor
contributes to roughly half of these cases. Oxidative stress (OS) has been identified as one …

Molecular changes induced by oxidative stress that impair human sperm motility

K Nowicka-Bauer, B Nixon - Antioxidants, 2020 - mdpi.com
A state of oxidative stress (OS) and the presence of reactive oxygen species (ROS) in the
male reproductive tract are strongly correlated with infertility. While physiological levels of …

Radiations and male fertility

KK Kesari, A Agarwal, R Henkel - Reproductive Biology and …, 2018 - Springer
During recent years, an increasing percentage of male infertility has to be attributed to an
array of environmental, health and lifestyle factors. Male infertility is likely to be affected by …

[HTML][HTML] Male subfertility and oxidative stress

EPP Evans, JTM Scholten, A Mzyk… - Redox biology, 2021 - Elsevier
To date 15% of couples are suffering from infertility with 45–50% of males being
responsible. With an increase in paternal age as well as various environmental and lifestyle …

The importance of oxidative stress in determining the functionality of mammalian spermatozoa: a two-edged sword

RJ Aitken, JR Drevet - Antioxidants, 2020 - mdpi.com
This article addresses the importance of oxidative processes in both the generation of
functional gametes and the aetiology of defective sperm function. Functionally, sperm …

Causes and consequences of oxidative stress in spermatozoa

RJ Aitken, Z Gibb, MA Baker, J Drevet… - Reproduction, Fertility …, 2016 - CSIRO Publishing
Spermatozoa are highly vulnerable to oxidative attack because they lack significant
antioxidant protection due to the limited volume and restricted distribution of cytoplasmic …

Effect of COVID-19 on male reproductive system–a systematic review

Y He, J Wang, J Ren, Y Zhao, J Chen… - Frontiers in …, 2021 - frontiersin.org
Background Angiotensin-converting enzyme II (ACE2), a receptor for Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) to enter host cells, is widely expressed …