The obligate intracellular human pathogen Chlamydia trachomatis undergoes a complex
developmental program involving transition between two forms: the infectious elementary …

Chlamydia trachomatis is the most common bacterial infection of the human reproductive
tract globally; however, the mechanisms underlying the adaptation of the organism to its …

The study of intracellular bacteria and nanometer-size membrane vesicles within infected
host cells poses an important challenge as it is difficult to identify each distinct population in …

Chlamydia trachomatis Scc4 (formerly CT663) engages the transcription machinery and the
pathogenic type III secretion system (T3SS). Both machines are required for Chlamydia …

Secretion of effector proteins into the eukaryotic host cell is required for Chlamydia
trachomatis virulence. In the infection process, Scc1 and Scc4, two chaperones of the type III …

Chlamydia trachomatis is an important human pathogen that undergoes a characteristic
development cycle correlating with stage-specific gene expression profiles. Taking …

目的通过建立细菌双杂交技术, 筛选MRSA 中与PBP2a 相互作用的蛋白. 方法利用PCR 扩增,
获得PBP2a 蛋白转肽酶活性区(TPase) 的编码基因, 插入pRBR 构建成诱饵质粒pBR-PBP2a …

目的分析沙眼衣原体隐匿质粒编码蛋白的相互作用. 方法采用基因克隆的方法将沙眼衣原体质粒
基因pgp1~ 4 及pgp8 分别克隆到pRAC 和pRBR 上, 通过转录激活细菌双杂交系统分析蛋白 …

Chlamydia trachomatis is an obligate intracellular microbe that is responsible for trachoma
and chlamydia in much of the developing world, but is difficult to manipulate due to its …

__________________________________… Background: The type III secretion (T3S)
chaperone Scc4 modulates Chlamydia RNA polymerase holoenzyme activity and is also …