[HTML][HTML] SARS-CoV-2 and innate immunity: the good, the bad, and the “goldilocks”

BL Sievers, MTK Cheng, K Csiba, B Meng… - Cellular & Molecular …, 2024 - nature.com
An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of
immunity. Knowledge about this interplay can not only help us identify biological …

mRNA vaccines: The future of prevention of viral infections?

P Rzymski, A Szuster‐Ciesielska… - Journal of medical …, 2023 - Wiley Online Library
Messenger RNA (mRNA) vaccines against COVID‐19 are the first authorized biological
preparations developed using this platform. During the pandemic, their administration has …

Efficacy and safety of 5-day oral Ensitrelvir for patients with mild to moderate COVID-19: the SCORPIO-SR randomized clinical trial

H Yotsuyanagi, N Ohmagari, Y Doi, M Yamato… - JAMA network …, 2024 - jamanetwork.com
Importance Treatment options for COVID-19 are warranted irrespective of the presence of
risk factors for severe disease. Objective To assess the efficacy and safety of ensitrelvir in …

Vaccination, immunity, and the changing impact of COVID-19 on infant health

F Torche, J Nobles - … of the National Academy of Sciences, 2023 - National Acad Sciences
In utero exposure to COVID-19 infection may lead to large intergenerational health effects.
The impact of infection exposure has likely evolved since the onset of the pandemic as new …

Effect of thromboprophylaxis on clinical outcomes after COVID-19 hospitalization

TY Wang, AS Wahed, A Morris… - Annals of internal …, 2023 - acpjournals.org
Background: Patients hospitalized with COVID-19 have an increased incidence of
thromboembolism. The role of extended thromboprophylaxis after hospital discharge is …

Overview of autoantibodies in COVID‐19 convalescents

K Dobrowolska, D Zarębska‐Michaluk… - Journal of medical …, 2023 - Wiley Online Library
Accumulating evidence shows that SARS‐CoV‐2 can potentially trigger autoimmune
processes, which can be responsible for the long‐term consequences of COVID‐19 …

[HTML][HTML] Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity

Z Yang, BA Johnson, VA Meliopoulos, X Ju, P Zhang… - Cell reports, 2024 - cell.com
Summary G3BP1/2 are paralogous proteins that promote stress granule formation in
response to cellular stresses, including viral infection. The nucleocapsid (N) protein of …

[HTML][HTML] Change in the clinical picture of hospitalized patients with COVID-19 between the early and late period of dominance of the omicron SARS-CoV-2 variant

R Flisiak, D Zarębska-Michaluk, K Dobrowolska… - Journal of Clinical …, 2023 - mdpi.com
This study aimed to compare the clinical picture of COVID-19 in the initial and later period of
Omicron dominance and to identify populations still at risk. A retrospective comparison of the …

[HTML][HTML] Immune interaction between SARS-CoV-2 and Mycobacterium tuberculosis

P Booysen, KA Wilkinson, D Sheerin, R Waters… - Frontiers in …, 2023 - frontiersin.org
SARS-CoV-2 and Mycobacterium tuberculosis (Mtb) are major infectious causes of death,
with meta-analyses and population-based studies finding increased mortality in co-infected …

[HTML][HTML] Comparing SARS-CoV-2 variants among children and adolescents in Germany: relative risk of COVID-19-related hospitalization, ICU admission and mortality

M Jank, AL Oechsle, J Armann, U Behrends, R Berner… - Infection, 2023 - Springer
Purpose SARS-CoV-2 infections cause COVID-19 and have a wide spectrum of morbidity.
Severe disease courses among children are rare. To date, data on the variability of morbidity …