Excitotoxicity induced by NMDA receptor‐mediated intracellular Ca2+ ([Ca2+] i) overload is
a major cause of delayed neuronal death in cerebral ischemia. Transient receptor potential …

Abstract Calcium (Ca 2+) is a ubiquitous second messenger that performs significant
physiological task such as neurosecretion, exocytosis, neuronal growth/differentiation, and …

Estradiol (E2) has been proven to be effective in treating perimenopausal depression (PD);
however, the downstream signaling pathways have not been fully elucidated. Transient …

Chemokine (CC motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein-1,
plays a critical role in leukocyte recruitment and activation. In the present study, we identify …

Ca 2+ signaling in neurons is intimately associated with the regulation of vital physiological
processes including growth, survival and differentiation. In neurons, Ca 2+ elicits two major …

Transient receptor potential canonical (TRPC) channels are Ca 2+-permeable, nonselective
cation channels formed by homomeric or heteromeric complexes of TRPC proteins that …

The activation and involvement of human endogenous retroviruses W family envelope gene
(HERV-W env, also called ERVWE1) have been reported in several neuropsychiatric …

Although it has been well documented that drugs of abuse such as cocaine cause enhanced
progression of human immunodeficiency virus (HIV)-associated neuropathological …

Platelet-derived growth factor-BB (PDGF) has been reported to provide tropic support for
neurons in the central nervous system. The protective role of PDGF on dopaminergic …

Background Brain-derived neurotrophic factor (BDNF) is believed to be an important
regulator of striatal neuron survival, differentiation, and plasticity. Moreover, reduction of …