Variant Philadelphia translocations: molecular-cytogenetic characterization and prognostic influence on frontline imatinib therapy, a GIMEMA Working Party on CML …
G Marzocchi, F Castagnetti, S Luatti… - Blood, The Journal …, 2011 - ashpublications.org
Abstract Variant Philadelphia (Ph) chromosome translocations have been reported in 5%-
10% of patients with newly diagnosed chronic myeloid leukemia (CML). Variant …
10% of patients with newly diagnosed chronic myeloid leukemia (CML). Variant …
New insights into the pathobiology and treatment of chronic myelogenous leukemia
CV Cotta, CE Bueso-Ramos - Annals of Diagnostic Pathology, 2007 - Elsevier
Chronic myelogenous leukemia (CML) is one of the most frequently diagnosed forms of
leukemia. Recent advances in the understanding of the molecular mechanisms involved in …
leukemia. Recent advances in the understanding of the molecular mechanisms involved in …
Monitoring response and resistance to treatment in chronic myeloid leukemia
S Assouline, JH Lipton - Current Oncology, 2011 - mdpi.com
Chronic myeloid leukemia (CML) results from expression of the constitutive tyrosine kinase
activity of the Bcr-Abl oncoprotein. Imatinib, a tyrosine kinase inhibitor (TKI), is highly …
activity of the Bcr-Abl oncoprotein. Imatinib, a tyrosine kinase inhibitor (TKI), is highly …
Precision Isolation of Circulating Leukemia Cells in Chronic Myelogenous Leukemia Patients Using a Novel Microfluidic Device and Its Clinical Applications
D Ouyang, N Ye, K Yang, Y Wang, L Hu, S Chao… - Cancers, 2023 - mdpi.com
Simple Summary Chronic Myelogenous Leukemia (CML) is a common blood cancer that
involves the uncontrolled growth of certain blood cells. Treating this disease effectively …
involves the uncontrolled growth of certain blood cells. Treating this disease effectively …
Detection of DNA fusion junctions for BCR-ABL translocations by Anchored ChromPET
Y Shibata, A Malhotra, A Dutta - Genome Medicine, 2010 - Springer
Anchored ChromPET, a technique to capture and interrogate targeted sequences in the
genome, has been developed to identify chromosomal aberrations and define breakpoints …
genome, has been developed to identify chromosomal aberrations and define breakpoints …
Efficacy and safety profile of generic imatinib in patients with newly diagnosed chronic myeloid leukemia-chronic phase: sharing experience of a hemato-oncology …
A Phukan, PK Mandal, TK Dolai - Annals of Hematology, 2021 - Springer
In India, CML is the commonest adult leukemia. Imatinib is the gold standard for frontline
treatment of newly diagnosed CML-CP patients. The present study was conducted to assess …
treatment of newly diagnosed CML-CP patients. The present study was conducted to assess …
A simple fluorescence biosensing strategy for ultrasensitive detection of the BCR–ABL1 fusion gene based on a DNA machine and multiple primer-like rolling circle …
H Wu, X Zhou, W Cheng, T Yuan, M Zhao, X Duan… - Analyst, 2018 - pubs.rsc.org
A one-step, rapid fluorescence biosensing method has been developed for ultrasensitive
detection of the BCR–ABL1 fusion gene based on a polymerase/nicking endonuclease DNA …
detection of the BCR–ABL1 fusion gene based on a polymerase/nicking endonuclease DNA …
Selective and sensitive detection of chronic myeloid leukemia using fluorogenic DNAzyme probes
X Geng, M Zhang, X Wang, J Sun, X Zhao, L Zhang… - Analytica Chimica …, 2020 - Elsevier
One of the major challenges facing the early diagnosis of chronic myelogenous leukemia
(CML) patients today is enhancing the simplicity, rapidness, sensitivity and specificity of …
(CML) patients today is enhancing the simplicity, rapidness, sensitivity and specificity of …
Chronic idiopathic myelofibrosis (CIMF) resulting from a unique 3; 9 translocation disrupting the janus kinase 2 (JAK2) gene
HFL Mark, EA Sotomayor, M Nelson, F Chaves… - … and molecular pathology, 2006 - Elsevier
We report a case of t (3; 9)(q21; p24) in a patient with chronic idiopathic myelofibrosis
(CIMF), a chronic myeloproliferative disorder (CMPD), initially detected by G-banding and …
(CIMF), a chronic myeloproliferative disorder (CMPD), initially detected by G-banding and …
Gambogic acid induces death of K562 cells through autophagy and apoptosis mechanisms
J Chen, M Zhou, Q Zhang, J Xu… - Leukemia & Lymphoma, 2015 - Taylor & Francis
This study was aimed to detect the effects of gambogic acid (GA) on the growth of chronic
myelogenous leukemia (CML) K562 cells. Our results showed that GA induced the …
myelogenous leukemia (CML) K562 cells. Our results showed that GA induced the …