The Diversity of Escherichia coli Pathotypes and Vaccination Strategies against This Versatile Bacterial Pathogen

P Pokharel, S Dhakal, CM Dozois - Microorganisms, 2023 - mdpi.com
Escherichia coli (E. coli) is a gram-negative bacillus and resident of the normal intestinal
microbiota. However, some E. coli strains can cause diseases in humans, other mammals …

Genomics and pathotypes of the many faces of Escherichia coli

J Geurtsen, M de Been, E Weerdenburg… - FEMS microbiology …, 2022 - academic.oup.com
Escherichia coli is the most researched microbial organism in the world. Its varied impact on
human health, consisting of commensalism, gastrointestinal disease, or extraintestinal …

Groundwater quality and public health

X Xie, J Shi, K Pi, Y Deng, B Yan, L Tong… - Annual Review of …, 2023 - annualreviews.org
Groundwater deterioration due to enrichment with contaminants of either geogenic or
anthropogenic origin has adversely affected safe water supply for drinking and irrigation …

Enterotoxigenic Escherichia coli: intestinal pathogenesis mechanisms and colonization resistance by gut microbiota

Y Zhang, P Tan, Y Zhao, X Ma - Gut Microbes, 2022 - Taylor & Francis
Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrhea in children and
travelers in developing countries. ETEC is characterized by the ability to produce major …

A low-cost, thermostable, cell-free protein synthesis platform for on-demand production of conjugate vaccines

KF Warfel, A Williams, DA Wong, SE Sobol… - ACS synthetic …, 2022 - ACS Publications
Cell-free protein synthesis systems that can be lyophilized for long-term, non-refrigerated
storage and transportation have the potential to enable decentralized biomanufacturing …

Combating the menace of antimicrobial resistance in Africa: a review on stewardship, surveillance and diagnostic strategies

BH Gulumbe, UA Haruna, J Almazan… - Biological procedures …, 2022 - Springer
The emergence of antibiotic-resistant pathogens has threatened not only our ability to deal
with common infectious diseases but also the management of life-threatening complications …

Controlled human infection models to accelerate vaccine development

RKM Choy, AL Bourgeois… - Clinical Microbiology …, 2022 - Am Soc Microbiol
The timelines for developing vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …

Pathogen contamination of groundwater systems and health risks

Y Dong, Z Jiang, Y Hu, Y Jiang, L Tong… - Critical Reviews in …, 2024 - Taylor & Francis
Groundwater has been a relatively safe water source and associated with a series of global
pressing issues. It can, however, be vulnerable to pathogen contamination and exhibit risks …

Guanylate cyclase-C Signaling Axis as a theragnostic target in colorectal cancer: a systematic review of literature

M Piroozkhah, A Aghajani, P Jalali… - Frontiers in …, 2023 - frontiersin.org
Introduction Colorectal cancer (CRC) is a devastating disease that affects millions of people
worldwide. Recent research has highlighted the crucial role of the guanylate cyclase-C (GC …

[HTML][HTML] Vaccine value profile for enterotoxigenic Escherichia coli (ETEC)

I Khalil, JD Anderson, KH Bagamian, S Baqar… - Vaccine, 2023 - Elsevier
Enterotoxigenic Escherichia coli (ETEC) is one of the leading bacterial causes of diarrhoea,
especially among children in low-resource settings, and travellers and military personnel …