Mild cognitive impairment (MCI) is a clinical condition with a high risk of progression to
dementia. Due to lack of effective disease-modifying therapies for advanced dementia …

Background This study aims to determine the relationship between diabetic retinopathy (DR)
and cognitive dysfunction as well as explores the effects of DR on different cognitive …

Background: Aging is associated with numerous stressors that negatively impact older
adults' well-being. Resilience improves ability to cope with stressors and can be enhanced …

Brain-predicted age difference scores are calculated by subtracting chronological age from
'brain'age, which is estimated using neuroimaging data. Positive scores reflect accelerated …

Introduction The locus coeruleus (LC) undergoes extensive neurodegeneration in early
Alzheimer's disease (AD). The LC is implicated in regulating the sleep–wake cycle …

Importance Subjective memory concern has long been considered a state-related indicator
of impending cognitive decline or dementia. The possibility that subjective memory concern …

Background: There are detectable cognitive differences in cognitively unimpaired (CU)
individuals with preclinical Alzheimer's disease (AD). Objective: To determine whether cross …

Executive function encompasses effortful cognitive processes that are particularly
susceptible to aging. Functional brain networks supporting executive function—such as the …

Objective: Alzheimer's disease (AD) is highly heritable, and AD polygenic risk scores (AD-
PRSs) have been derived from genome-wide association studies. However, the nature of …

Introduction The aim of this study was to develop a conditional normative model for Rey's
Auditory Verbal Learning Test (AVLT) that accounts for practice effects. Methods In our …