Cell Death–associated ADAMTS4 and Versican Degradation in Vascular Tissue

RD Kenagy, SK Min, AW Clowes… - … of Histochemistry & …, 2009 - journals.sagepub.com
High blood flow through baboon polytetrafluorethylene aorto-iliac grafts increases
neointimal vascular smooth muscle cell (SMC) death, neointimal atrophy, and cleavage of …

Cutting edge: two distinct motifs within the Fas ligand tail regulate Fas ligand-mediated costimulation

M Sun, S Lee, S Karray, M Levi-Strauss… - The Journal of …, 2007 - journals.aai.org
The cytoplasmic domain of Fas ligand is sufficient to costimulate CD8+ T cells by driving Fas
ligand recruitment into lipid rafts and association with select Src homology 3-containing …

Induction of apoptosis in breast cancer cells in vitro by Fas ligand reverse signaling

T Kolben, U Jeschke, T Reimer, N Karsten… - Journal of cancer …, 2018 - Springer
Abstract Purpose The Fas-antigen is a cell surface receptor that transduces apoptotic
signals into cells. The purpose of this study was to evaluate FasL expression in breast …

FasL expression and reverse signalling

M Lettau, M Paulsen, D Kabelitz, O Janssen - Death Receptors and …, 2009 - Springer
FasL plays a central role in the induction of apoptosis within the immune system. It mediates
activation-induced cell death (AICD) of T lymphocytes and contributes to the cytotoxic …

Critical role of lipid rafts in CD154‐mediated T cell signaling

Y El Fakhry, H Alturaihi, D Diallo… - European journal of …, 2010 - Wiley Online Library
Although signal pathways triggered via the CD40 molecule are well characterized, those
induced via CD154 are less known. This study demonstrates that engagement of CD154 in …

[HTML][HTML] Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening

M Voss, M Lettau, O Janssen - BMC immunology, 2009 - Springer
Background-Fas ligand is a cytotoxic effector molecule of T and NK cells which is
characterized by an intracellular N-terminal polyproline region that serves as a docking site …

Targeting Fas in osteoresorptive disorders

N Kovacic, D Grcevic, V Katavic, IK Lukic… - Expert opinion on …, 2010 - Taylor & Francis
Importance of the field: Fas receptor is a mediator of the external apoptotic pathway in many
cells and tissues. It is proposed that Fas receptor mediates osteoresorptive effects of …

[HTML][HTML] Fas ligand enhances malignant behavior of tumor cells through interaction with Met, hepatocyte growth factor receptor, in lipid rafts

HC Lin, PY Lai, Y Lin, JY Huang, BC Yang - Journal of Biological Chemistry, 2012 - ASBMB
Many late-stage cancer cells express Fas ligand (FasL) and show high malignancy with
metastatic potential. We report here a novel signaling mechanism for FasL that hijacks the …

[HTML][HTML] No evidence that soluble TACI induces signalling via membrane-expressed BAFF and APRIL in myeloid cells

J Nys, CR Smulski, A Tardivel, L Willen, C Kowalczyk… - PLoS …, 2013 - journals.plos.org
Myeloid cells express the TNF family ligands BAFF/BLyS and APRIL, which exert their
effects on B cells at different stages of differentiation via the receptors BAFFR, TACI …

[HTML][HTML] A proteomic screen reveals novel Fas ligand interacting proteins within nervous system Schwann cells

PB Thornhill, JB Cohn, G Drury, WL Stanford… - FEBS letters, 2007 - Elsevier
Fas ligand (FasL) binds Fas (CD95) to induce apoptosis or activate other signaling
pathways. In addition, FasL transduces bidirectional or 'reverse signals'. The intracellular …