Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child

PM Catalano, K Shankar - Bmj, 2017 - bmj.com
Obesity is the most common medical condition in women of reproductive age. Obesity during
pregnancy has short term and long term adverse consequences for both mother and child …

Inflammation in maternal obesity and gestational diabetes mellitus

P Pantham, ILMH Aye, TL Powell - Placenta, 2015 - Elsevier
Background The prevalence of maternal obesity is rising rapidly worldwide and constitutes a
major obstetric problem, increasing mortality and morbidity in both mother and offspring …

Pathophysiology and current clinical management of preeclampsia

LM Amaral, K Wallace, M Owens, B LaMarca - Current hypertension …, 2017 - Springer
Preeclampsia is characterized by blood pressure greater than 140/90 mmHg in the second
half of pregnancy. This disease is a major contributor to preterm and low birth weight babies …

Placental function in maternal obesity

AC Kelly, TL Powell, T Jansson - Clinical Science, 2020 - portlandpress.com
Maternal obesity is associated with pregnancy complications and increases the risk for the
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …

Maternal obesity and neurodevelopmental and psychiatric disorders in offspring

AG Edlow - Prenatal diagnosis, 2017 - Wiley Online Library
There is a growing body of evidence from both human epidemiologic and animal studies
that prenatal and lactational exposure to maternal obesity and high‐fat diet are associated …

Overweight and obesity in pregnancy: their impact on epigenetics

C Reichetzeder - European journal of clinical nutrition, 2021 - nature.com
Over the last few decades, the prevalence of obesity has risen to epidemic proportions
worldwide. Consequently, the number of obesity in pregnancy has risen drastically …

Angiogenesis in the placenta: the role of reactive oxygen species signaling

RD Pereira, NE De Long, RC Wang… - BioMed research …, 2015 - Wiley Online Library
Proper placental development and function are central to the health of both the mother and
the fetus during pregnancy. A critical component of healthy placental function is the proper …

Maternal low-grade chronic inflammation and intrauterine programming of health and disease

F Parisi, R Milazzo, VM Savasi, I Cetin - International journal of molecular …, 2021 - mdpi.com
Overweight and obesity during pregnancy have been associated with increased birth
weight, childhood obesity, and noncommunicable diseases in the offspring, leading to a …

Mechanisms of endothelial dysfunction in pre-eclampsia and gestational diabetes mellitus: windows into future cardiometabolic health?

CJ McElwain, E Tuboly, FP McCarthy… - Frontiers in …, 2020 - frontiersin.org
Placental insufficiency and adipose tissue dysregulation are postulated to play key roles in
the pathophysiology of both pre-eclampsia (PE) and gestational diabetes mellitus (GDM). A …

Maternal obesity and the impact of associated early-life inflammation on long-term health of offspring

M Denizli, ML Capitano, KL Kua - Frontiers in cellular and infection …, 2022 - frontiersin.org
The prevalence of obesity is increasingly common in the United States, with~ 25% of women
of reproductive age being overweight or obese. Metaflammation, a chronic low grade …