The importance of biological sex and estrogen in rodent models of cardiovascular health and disease

CL Blenck, PA Harvey, JF Reckelhoff… - Circulation …, 2016 - Am Heart Assoc
Nearly one-third of deaths in the United States are caused by cardiovascular disease (CVD)
each year. In the past, CVD was thought to mainly affect men, leading to the exclusion of …

In-silico modeling of the functional role of reduced sialylation in sodium and potassium channel gating of mouse ventricular myocytes

D Du, H Yang, AR Ednie… - IEEE journal of biomedical …, 2017 - ieeexplore.ieee.org
Cardiac ion channels are highly glycosylated membrane proteins with up to 30% of the
protein's mass containing glycans. Heart diseases often accompany individuals with …

Structural variant calling by assembly in whole human genomes: Applications in hypoplastic left heart syndrome

M Kendzior - 2019 - ideals.illinois.edu
Variant discovery in medical research typically involves alignment of short sequencing reads
to the human reference genome. SNPs and small indels (variants less than 50 nucleotides) …