Individual risk management strategy and potential therapeutic options for the COVID-19 pandemic
It is an ugly fact that a significant amount of the world's population will contract SARS-CoV-II
infection with the current spreading. While a specific treatment is not yet coming soon …
infection with the current spreading. While a specific treatment is not yet coming soon …
RNA-dependent RNA polymerase as a target for COVID-19 drug discovery
W Zhu, CZ Chen, K Gorshkov, M Xu… - … the Science of Drug …, 2020 - journals.sagepub.com
COVID-19 respiratory disease caused by the severe acute respiratory syndrome coronavirus-
2 (SARS-CoV-2) has rapidly become a global health issue since it emerged in December …
2 (SARS-CoV-2) has rapidly become a global health issue since it emerged in December …
Discovery of potential multi-target-directed ligands by targeting host-specific SARS-CoV-2 structurally conserved main protease
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in
the current COVID-19 pandemic. Worldwide this disease has infected over 2.5 million …
the current COVID-19 pandemic. Worldwide this disease has infected over 2.5 million …
The SARS-coronavirus infection cycle: a survey of viral membrane proteins, their functional interactions and pathogenesis
NA Wong, MH Saier Jr - International journal of molecular sciences, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a novel epidemic
strain of Betacoronavirus that is responsible for the current viral pandemic, coronavirus …
strain of Betacoronavirus that is responsible for the current viral pandemic, coronavirus …
[HTML][HTML] Antivirals for COVID-19: a critical review
No specific drugs have been approved for coronavirus disease 2019 (COVID-19) to date as
the development of antivirals usually requires time. Therefore, assessment and use of …
the development of antivirals usually requires time. Therefore, assessment and use of …
COVID-19, cytokines, inflammation, and spices: How are they related?
Background Cytokine storm is the exaggerated immune response often observed in viral
infections. It is also intimately linked with the progression of COVID-19 disease as well as …
infections. It is also intimately linked with the progression of COVID-19 disease as well as …
[HTML][HTML] The journey of remdesivir: from Ebola to COVID-19
J Pardo, AM Shukla, G Chamarthi, A Gupte - Drugs in context, 2020 - ncbi.nlm.nih.gov
Countries around the world are currently fighting the coronavirus disease 2019 (COVID-19)
pandemic, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
pandemic, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
Remdesivir for treatment of COVID-19; an updated systematic review and meta-analysis
Abstract The coronavirus disease 2019 (COVID-19) pandemic has become a global health
crisis. Considering the recent food and drug administration (FDA) approval of remdesivir as …
crisis. Considering the recent food and drug administration (FDA) approval of remdesivir as …
[HTML][HTML] RdRp inhibitors and COVID-19: Is molnupiravir a good option?
SMR Hashemian, MH Pourhanifeh, MR Hamblin… - Biomedicine & …, 2022 - Elsevier
Rapid changes in the viral genome allow viruses to evade threats posed by the host immune
response or antiviral drugs, and can lead to viral persistence in the host cells. RNA …
response or antiviral drugs, and can lead to viral persistence in the host cells. RNA …
[HTML][HTML] Comprehensive analysis of drugs to treat SARS‑CoV‑2 infection: Mechanistic insights into current COVID‑19 therapies
GM Nitulescu, H Paunescu… - International …, 2020 - spandidos-publications.com
The major impact produced by the severe acute respiratory syndrome coronavirus 2 (SARS‑
CoV‑2) focused many researchers attention to find treatments that can suppress …
CoV‑2) focused many researchers attention to find treatments that can suppress …