Interactome battling of lncRNA CCDC144NL-AS1: Its role in the emergence and ferocity of cancer and beyond

YK Abd El Fattah, AI Abulsoud, SG AbdelHamid… - International Journal of …, 2022 - Elsevier
Long non-coding RNAs (lncRNAs) were, once, viewed as “noise” for transcription. Recently,
many lncRNAs are functionally linked to several human disorders, including cancer. Coiled …

[HTML][HTML] Functional interaction among lncRNA HOTAIR and microRNAs in cancer and other human diseases

M Cantile, M Di Bonito, M Tracey De Bellis, G Botti - Cancers, 2021 - mdpi.com
Simple Summary This review aimed to describe the contribution of functional interaction
between the lncRNA HOTAIR and microRNAs in human diseases, including cancer …

lncRNAfunc: a knowledgebase of lncRNA function in human cancer

M Yang, H Lu, J Liu, S Wu, P Kim… - Nucleic acids research, 2022 - academic.oup.com
The long non-coding RNAs associating with other molecules can coordinate several
physiological processes and their dysfunction can impact diverse human diseases. To date …

[HTML][HTML] Signaling by LncRNAs: Structure, cellular homeostasis, and disease pathology

R Nadhan, C Isidoro, YS Song, DN Dhanasekaran - Cells, 2022 - mdpi.com
The cellular signaling network involves co-ordinated regulation of numerous signaling
molecules that aid the maintenance of cellular as well as organismal homeostasis. Aberrant …

RNA-binding proteins and their role in kidney disease

L Seufert, T Benzing, M Ignarski… - Nature Reviews …, 2022 - nature.com
RNA-binding proteins (RBPs) are of fundamental importance for post-transcriptional gene
regulation and protein synthesis. They are required for pre-mRNA processing and for RNA …

[HTML][HTML] Long non-coding RNAs in cardiovascular diseases: potential function as biomarkers and therapeutic targets of exercise training

CCM Correia, LF Rodrigues, BR de Avila Pelozin… - Non-coding RNA, 2021 - mdpi.com
Despite advances in treatments and therapies, cardiovascular diseases (CVDs) remain one
of the leading causes of death worldwide. The discovery that most of the human genome …

A comprehensive survey on computational methods of non-coding RNA and disease association prediction

X Lei, TB Mudiyanselage, Y Zhang… - Briefings in …, 2021 - academic.oup.com
The studies on relationships between non-coding RNAs and diseases are widely carried out
in recent years. A large number of experimental methods and technologies of producing …

[HTML][HTML] Long non-coding RNA epigenetics

M Kazimierczyk, J Wrzesinski - International Journal of Molecular …, 2021 - mdpi.com
Long noncoding RNAs exceeding a length of 200 nucleotides play an important role in
ensuring cell functions and proper organism development by interacting with cellular …

Exosomal lncRNA PVT1/VEGFA axis promotes colon cancer metastasis and stemness by downregulation of tumor suppressor miR‐152‐3p

SW Lai, MY Chen, OA Bamodu… - Oxidative Medicine …, 2021 - Wiley Online Library
Background. Treating advanced colon cancer remains challenging in clinical settings
because of the development of drug resistance and distant metastasis. Mechanisms …

lncRNA MALAT1 Regulates the Resistance of Breast Cancer Cells to Paclitaxel Via the miR-497-5p/ SHOC2 axis

C Shi, S Ren, X Zhao, Q Li - Pharmacogenomics, 2022 - Taylor & Francis
Aim: To explore the roles of lncRNA MALAT1 and SHOC2 in breast cancer, and the potential
connections to chemotherapy resistance in breast cancer. Materials & methods: Paclitaxel …