Losartan is an angiotensin II receptor blocker (ARB) that impedes transforming growth factor
(TGF) beta signaling by inhibiting activation of signal transduction molecule extracellular …

Reducing the morbidities caused by neglected tropical diseases (NTDs) is a central aim of
ongoing disease control programmes. The broad spectrum of pathogens under the umbrella …

The obligate intracellular bacterium Chlamydia trachomatis inserts a family of inclusion
membrane (Inc) proteins into the membrane of its vacuole (the inclusion). The Inc CpoS is a …

Diseases caused by Chlamydia spp. are often associated with persistent infections.
Chlamydial persistence is commonly associated with a unique non-infectious intracellular …

Background There is no vaccine against the major global pathogen Chlamydia trachomatis;
its different serovars cause trachoma in the eye or chlamydia in the genital tract. We did a …

Chlamydia trachomatis, one species of Chlamydia spp., has the greatest impact on human
health and is the main cause of bacterial sexually transmitted diseases and preventable …

Ocular, genital, and anogenital infection by the obligate intracellular pathogen Chlamydia
trachomatis have been consistently associated with scar-forming sequelae. In cases of …

Purpose Population-based prevalence surveys are essential for decision-making on
interventions to achieve trachoma elimination as a public health problem. This paper …

Background Trachoma is the commonest infectious cause of blindness worldwide. Efforts
are being made to eliminate trachoma as a public health problem globally. However, as …

Mitochondria are critical cellular organelles that perform a wide variety of functions,
including energy production and immune regulation. To perform these functions …