[HTML][HTML] The importance of protein domain mutations in cancer therapy

CK Kumar, A Emerson - Heliyon, 2024 - cell.com
Cancer is a complex disease that is caused by multiple genetic factors. Researchers have
been studying protein domain mutations to understand how they affect the progression and …

The latest research progress on P53 and tumor metabolism

Z Haihui, LIU Yuanqi, Z Congzheng, G Liping… - China …, 2023 - china-oncology.com
P53 is a key factor encoded by the TP53, and it prevents cells from becoming cancerous and
has a wide range of powerful functions. p53 is found to play an important role in inducing …

The p53 tumor suppressor protein activates transcription of DUSP13 isoform from the alternative promoter in intron 3

M Krześniak, B Łasut-Szyszka, A Będzińska… - 2023 - preprints.org
The p53 tumor suppressor protein is an activator of transcription. Diverse stress factors lead
to various sets of posttranslational modifications of p53 what results in different sets of …