Immunoinformatics and vaccine development: an overview

AN Oli, WO Obialor, MO Ifeanyichukwu… - ImmunoTargets and …, 2020 - Taylor & Francis
The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …

[HTML][HTML] Reverse vaccinology: an approach for identifying leptospiral vaccine candidates

OA Dellagostin, AA Grassmann, C Rizzi… - International Journal of …, 2017 - mdpi.com
Leptospirosis is a major public health problem with an incidence of over one million human
cases each year. It is a globally distributed, zoonotic disease and is associated with …

[HTML][HTML] Promising new vaccine candidates against Campylobacter in broilers

M Meunier, M Guyard-Nicodème, E Vigouroux… - PloS one, 2017 - journals.plos.org
Campylobacter is the leading cause of human bacterial gastroenteritis in the European
Union. Birds represent the main reservoir of the bacteria, and human campylobacteriosis …

[HTML][HTML] Monoclonal Antibodies as a Therapeutic Strategy against Multidrug-Resistant Bacterial Infections in a Post-COVID-19 Era

HC Chen, YL Pan, Y Chen, TH Yang, ET Hsu… - Life, 2024 - mdpi.com
The development of severe multidrug-resistant bacterial infections has recently intensified
because of the COVID-19 pandemic. According to the guidelines issued by the World Health …

[HTML][HTML] Immunogenicity of trimeric autotransporter adhesins and their potential as vaccine targets

A Thibau, AA Dichter, DJ Vaca, D Linke… - Medical Microbiology …, 2020 - Springer
The current problem of increasing antibiotic resistance and the resurgence of numerous
infections indicate the need for novel vaccination strategies more than ever. In vaccine …

[HTML][HTML] Subtractive Proteomics and Immuno-informatics Approaches for Multi-peptide Vaccine Prediction Against Klebsiella oxytoca and Validation Through In Silico …

Q Yousafi, H Amin, S Bibi, R Rafi, MS Khan… - International Journal of …, 2021 - Springer
Klebsiella oxytoca is a gram-negative bacterium. It is opportunistic in nature and causes
hospital acquired infections. Subtractive proteomics and reverse vaccinology approaches …

Modified mRNA-based vaccines against coronavirus disease 2019

AYL Wang - Cell transplantation, 2022 - journals.sagepub.com
The pandemic of coronavirus disease 2019 (COVID-19) continuously causes deaths
worldwide, representing a considerable challenge to health care and economic systems …

[HTML][HTML] A qualitatively validated mathematical-computational model of the immune response to the yellow fever vaccine

CRB Bonin, GC Fernandes, RW Dos Santos… - BMC immunology, 2018 - Springer
Background Although a safe and effective yellow fever vaccine was developed more than 80
years ago, several issues regarding its use remain unclear. For example, what is the …

[HTML][HTML] Potential Antigenic Candidates for the Development of Peptide-Based Vaccines to Induce Immunization against Helicobacter pylori Infection in BALB/c Mice

DM AlEraky, HM Abuohashish, AS Bugshan… - International Journal of …, 2022 - mdpi.com
Helicobacter pylori (H. pylori) has been identified as a group-1 definite carcinogen. As of yet,
there is no available vaccine for this microorganism. Our study aimed to identify antigenic …

[HTML][HTML] A new workflow to generate monoclonal antibodies against microorganisms

M Göthel, M Listek, K Messerschmidt, A Schlör… - Applied Sciences, 2021 - mdpi.com
Monoclonal antibodies are used worldwide as highly potent and efficient detection reagents
for research and diagnostic applications. Nevertheless, the specific targeting of complex …