From single-to multi-omics: future research trends in medicinal plants

L Yang, Y Yang, L Huang, X Cui… - Briefings in bioinformatics, 2023 - academic.oup.com
Medicinal plants are the main source of natural metabolites with specialised
pharmacological activities and have been widely examined by plant researchers. Numerous …

Multilayered regulation of secondary metabolism in medicinal plants

Y Zhao, G Liu, F Yang, Y Liang, Q Gao, C Xiang… - Molecular …, 2023 - Springer
Medicinal plants represent a huge reservoir of secondary metabolites (SMs), substances
with significant pharmaceutical and industrial potential. However, obtaining secondary …

Advances in the research on plant WRKY transcription factors responsive to external stresses

H Wang, X Cheng, D Yin, D Chen, C Luo, H Liu… - Current Issues in …, 2023 - mdpi.com
The WRKY transcription factors are a class of transcriptional regulators that are ubiquitous in
plants, wherein they play key roles in various physiological activities, including responses to …

[HTML][HTML] Decoding plant specialized metabolism: New mechanistic insights

Q Li, S Duncan, Y Li, S Huang, M Luo - Trends in Plant Science, 2024 - cell.com
Secondary metabolite (SM) production provides biotic and abiotic stress resistance and
enables plants to adapt to the environment. Biosynthesis of these metabolites involves a …

Optimization of Isolation and Transformation of Protoplasts from Uncaria rhynchophylla and Its Application to Transient Gene Expression Analysis

Y Shao, D Mu, L Pan, IW Wilson, Y Zheng… - International journal of …, 2023 - mdpi.com
Protoplast-based engineering has become an important tool for basic plant molecular
biology research and developing genome-edited crops. Uncaria rhynchophylla is a …

OpNAC1 transcription factor regulates the biosynthesis of the anticancer drug camptothecin by targeting loganic acid O‐methyltransferase in Ophiorrhiza pumila

X Hao, C Wang, W Zhou, Q Ruan, C Xie… - Journal of Integrative …, 2023 - Wiley Online Library
Camptothecin (CPT) is an anticancer pentacyclic quinoline alkaloid widely used to treat
cancer patients worldwide. However, the biosynthetic pathway and transcriptional regulation …

Genome-Wide Identification and Expression Analysis of WRKY Transcription Factors in Siraitia siamensis

D Mu, W Chen, Y Shao, IW Wilson, H Zhao, Z Luo… - Plants, 2023 - mdpi.com
WRKY transcription factors, as the largest gene family in higher plants, play an important
role in various biological processes including growth and development, regulation of …

Genome-Wide Identification and Characterization of WRKY Transcription Factors and Their Expression Profile in Loropetalum chinense var. rubrum

Y Liu, Y Zhang, Y Liu, L Lin, X Xiong, D Zhang, S Li… - Plants, 2023 - mdpi.com
The WRKY gene family plays important roles in plant growth and development, as well as in
the responses to biotic and abiotic stresses. Loropetalum chinense var. rubrum has high …

Evaluation of Reference Genes for Normalizing RT-qPCR and Analysis of the Expression Patterns of WRKY1 Transcription Factor and Rhynchophylline Biosynthesis-Related …

D Mu, Y Shao, J He, L Zhu, D Qiu, IW Wilson… - International Journal of …, 2023 - mdpi.com
Uncaria rhynchophylla (Miq.) Miq. ex Havil, a traditional medicinal herb, is enriched with
several pharmacologically active terpenoid indole alkaloids (TIAs). At present, no method …

Molecular regulation of the key specialized metabolism pathways in medicinal plants

M Shi, S Zhang, Z Zheng, I Maoz… - Journal of Integrative …, 2024 - Wiley Online Library
The basis of modern pharmacology is the human ability to exploit the production of
specialized metabolites from medical plants, for example, terpenoids, alkaloids, and …