Ulcerative colitis in adults: A review

B Gros, GG Kaplan - Jama, 2023 - jamanetwork.com
Importance Ulcerative colitis (UC) is a chronic inflammatory condition of the colon, with a
prevalence exceeding 400 per 100 000 in North America. Individuals with UC have a lower …

Mechanisms of mucosal healing: treating inflammatory bowel disease without immunosuppression?

EJ Villablanca, K Selin, CRH Hedin - Nature Reviews Gastroenterology …, 2022 - nature.com
Almost all currently available treatments for inflammatory bowel disease (IBD) act by
inhibiting inflammation, often blocking specific inflammatory molecules. However, given the …

European Crohn's and colitis guidelines on sexuality, fertility, pregnancy, and lactation

J Torres, M Chaparro, M Julsgaard… - Journal of Crohn's …, 2023 - academic.oup.com
2. Methods This document represents the third version of the European Consensus on
reproduction in IBD. The development of this Consensus included the formulation of …

Versatile carbon dots with superoxide dismutase-like nanozyme activity and red fluorescence for inflammatory bowel disease therapeutics

Y Ma, J Zhao, L Cheng, C Li, X Yan, Z Deng, Y Zhang… - Carbon, 2023 - Elsevier
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease
(CD), is a chronic and recurrent disease that seriously affects the life quality of patients …

[HTML][HTML] Vitamin D in inflammatory bowel diseases. Mechanisms of action and therapeutic implications

F Vernia, M Valvano, S Longo, N Cesaro, A Viscido… - Nutrients, 2022 - mdpi.com
(1) Background: Vitamin D is an immunoregulatory factor influencing intestinal homeostasis.
Recent evidence supports a central role of this micronutrient in the course of Inflammatory …

[HTML][HTML] An update on current pharmacotherapeutic options for the treatment of ulcerative colitis

F Ferretti, R Cannatelli, MC Monico, G Maconi… - Journal of Clinical …, 2022 - mdpi.com
The main goals of Ulcerative Colitis (UC) treatment are to both induce and maintain the
clinical and endoscopic remission of disease, reduce the incidence of complications such as …

[HTML][HTML] Colorectal cancer in ulcerative colitis: mechanisms, surveillance and chemoprevention

W Li, T Zhao, D Wu, J Li, M Wang, Y Sun, S Hou - Current Oncology, 2022 - mdpi.com
Patients with ulcerative colitis (UC) are at a two-to three-fold increased risk of developing
colorectal cancer (CRC) than the general population based on population-based data. UC …

Difficult-to-treat inflammatory bowel disease: results from an international consensus meeting

TL Parigi, F D'Amico, MT Abreu, A Dignass… - The Lancet …, 2023 - thelancet.com
Many patients with inflammatory bowel disease (IBD) have persistent symptoms and
disease activity despite the best available medical or surgical treatments. These patients are …

Proactive therapeutic drug monitoring versus conventional management for inflammatory bowel diseases: a systematic review and meta-analysis

NH Nguyen, V Solitano, SK Vuyyuru, JK MacDonald… - Gastroenterology, 2022 - Elsevier
Background & Aims Proactive therapeutic drug monitoring (TDM) has been proposed to
improve outcomes in patients with inflammatory bowel disease (IBD) treated with tumor …

[HTML][HTML] The second decade of anti-TNF-a therapy in clinical practice: New lessons and future directions in the COVID-19 era

G Evangelatos, G Bamias, GD Kitas, G Kollias… - Rheumatology …, 2022 - Springer
Since the late 1990s, tumor necrosis factor alpha (TNF-α) inhibitors (anti-TNFs) have
revolutionized the therapy of immune-mediated inflammatory diseases (IMIDs) affecting the …