Bromelain a potential bioactive compound: a comprehensive overview from a pharmacological perspective

AJ Chakraborty, S Mitra, TE Tallei, AM Tareq, F Nainu… - Life, 2021 - mdpi.com
Bromelain is an effective chemoresponsive proteolytic enzyme derived from pineapple
stems. It contains several thiol endopeptidases and is extracted and purified via several …

Mechanisms of osteoarthritis (OA) pain

TW O'Neill, DT Felson - Current osteoporosis reports, 2018 - Springer
Abstract Purpose of Review Osteoarthritis (OA) is a major cause of pain and disability
worldwide. There is, however, a relatively poor correlation between the severity of OA based …

Use of 2D U-Net convolutional neural networks for automated cartilage and meniscus segmentation of knee MR imaging data to determine relaxometry and …

B Norman, V Pedoia, S Majumdar - Radiology, 2018 - pubs.rsna.org
Purpose To analyze how automatic segmentation translates in accuracy and precision to
morphology and relaxometry compared with manual segmentation and increases the speed …

Epidemiology of chronic low back pain in US adults: data from the 2009–2010 National Health and Nutrition Examination Survey

A Shmagel, R Foley, H Ibrahim - Arthritis care & research, 2016 - Wiley Online Library
Objective To describe the epidemiologic characteristics and associations with increased
health care utilization in US adults with chronic low back pain (LBP). Methods The National …

The individual and socioeconomic impact of osteoarthritis

DJ Hunter, D Schofield, E Callander - Nature Reviews Rheumatology, 2014 - nature.com
Osteoarthritis (OA) is a highly prevalent, disabling disease, with a commensurate
tremendous individual and socioeconomic burden. This Perspectives article focuses on the …

Low back pain: clinical practice guidelines linked to the International Classification of Functioning, Disability, and Health from the Orthopaedic Section of the American …

A Delitto, SZ George, L Van Dillen, JM Whitman… - Journal of orthopaedic & …, 2012 - jospt.org
INTERVENTIONS-MANUAL THERAPY: Clinicians should consider utilizing thrust
manipulative procedures to reduce pain and disability in patients with mobility deficits and …

[PDF][PDF] Opioid epidemic in the United States

L Manchikanti, SHB Fellows, JW Janata… - Pain …, 2012 - painphysicianjournal.com
The purpose of this comprehensive review is to describe various aspects of crisis of opioid
use in the United States. The obstacles that must be surmounted are primarily inappropriate …

Body mass index and risk of knee osteoarthritis: systematic review and meta-analysis of prospective studies

H Zheng, C Chen - BMJ open, 2015 - bmjopen.bmj.com
Objectives Obesity is suggested to be a risk factor for knee osteoarthritis (OA). This meta-
analysis aimed to examine the relationship between body mass index (BMI) and the risk of …

The epidemiology of low back pain

D Hoy, P Brooks, F Blyth, R Buchbinder - Best practice & research Clinical …, 2010 - Elsevier
Low back pain is an extremely common problem that most people experience at some point
in their life. While substantial heterogeneity exists among low back pain epidemiological …

[HTML][HTML] Increased low back pain prevalence in females than in males after menopause age: evidences based on synthetic literature review

YXJ Wáng, JQ Wáng, Z Káplár - Quantitative imaging in medicine …, 2016 - ncbi.nlm.nih.gov
Female sex hormones play an important role in the etiology and pathophysiology of a variety
of musculoskeletal degenerative diseases. Postmenopausal women show accelerated disc …