The loss of vital cells within healthy tissues contributes to the development, progression and
treatment outcomes of many human disorders, including neurological and infectious …

DNA damage, largely owing to oxidative stress, is a leading cause of defective sperm
function. High levels of oxidative stress result in damage to sperm DNA, RNA transcripts …

Cadmium is a heavy toxic metal with unknown biological functions in the human body. Over
time, cadmium accretion in the different visceral organs (liver, lungs, kidney, and testis) is …

Summary N 6-methyladenosine (m 6 A) is the most prevalent internal modification of
messenger RNA (mRNA) in higher eukaryotes. Here we report ALKBH5 as another …

The process of spermatogenesis is temperature-dependent and occurs optimally at
temperatures slightly lower than that of the body. Adequate thermoregulation is imperative to …

The blood-testis barrier (BTB) is one of the tightest blood-tissue barriers in the mammalian
body. It divides the seminiferous epithelium into the basal and the apical (adluminal) …

Understanding the extent of genomic transcription and its functional relevance is a central
goal in genomics research. However, detailed genome-wide investigations of transcriptome …

Activation of caspase, externalization of phosphatidyl serine, change in the mitochondrial
membrane potential, and DNA fragmentation are apoptosis markers found in human …

Phagocytosis, a critical early event in the microbicidal response of neutrophils, is now
appreciated to serve multiple functions in a variety of cell types. Professional phagocytes …

Sperm DNA fragmentation (sDF) represents a threat to male fertility, human reproduction
and the health of the offspring. The causes of sDF are still unclear, even if apoptosis …