Digoxin: Pharmacology and toxicology—A review
Digoxin is a cardiac glycoside used as drug in case of heart problems, including congestive
heart failure, atrial fibrillation or flutter, and certain cardiac arrhythmias. It has a very narrow …
heart failure, atrial fibrillation or flutter, and certain cardiac arrhythmias. It has a very narrow …
The use of medicinal plant-derived metallic nanoparticles in theranostics
In the quest to effectively diagnose and treat the diseases that afflict mankind, the
development of a tool capable of simultaneous detection and treatment would provide a …
development of a tool capable of simultaneous detection and treatment would provide a …
Cardiac glycosides are broad-spectrum senolytics
A Guerrero, N Herranz, B Sun, V Wagner… - Nature …, 2019 - nature.com
Senescence is a cellular stress response that results in the stable arrest of old, damaged or
pre-neoplastic cells. Oncogene-induced senescence is tumour suppressive but can also …
pre-neoplastic cells. Oncogene-induced senescence is tumour suppressive but can also …
Multidisciplinary approaches identify compounds that bind to human ACE2 or SARS-CoV-2 spike protein as candidates to block SARS-CoV-2–ACE2 receptor …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged virus
that causes coronavirus infectious disease 2019 (COVID-19). SARS-CoV-2 spike protein …
that causes coronavirus infectious disease 2019 (COVID-19). SARS-CoV-2 spike protein …
Bright and early: Inhibiting human cytomegalovirus by targeting major immediate-early gene expression or protein function
CS Adamson, MM Nevels - Viruses, 2020 - mdpi.com
The human cytomegalovirus (HCMV), one of eight human herpesviruses, establishes
lifelong latent infections in most people worldwide. Primary or reactivated HCMV infections …
lifelong latent infections in most people worldwide. Primary or reactivated HCMV infections …
Natural compounds targeting glycolysis as promising therapeutics for gastric cancer: a review
M Zhao, F Wei, G Sun, Y Wen, J Xiang, F Su… - Frontiers in …, 2022 - frontiersin.org
Gastric cancer, a common malignant disease, seriously endangers human health and life.
The high mortality rate due to gastric cancer can be attributed to a lack of effective …
The high mortality rate due to gastric cancer can be attributed to a lack of effective …
Molecular Modes of Action of an Aqueous Nerium oleander Extract in Cancer Cells In Vitro and In Vivo
Cancer drug resistance remains a major obstacle in clinical oncology. As most anticancer
drugs are of natural origin, we investigated the anticancer potential of a standardized cold …
drugs are of natural origin, we investigated the anticancer potential of a standardized cold …
Co-targeting tumor angiogenesis and immunosuppressive tumor microenvironment: A perspective in ethnopharmacology
J Zhou, L Wang, C Peng, F Peng - Frontiers in Pharmacology, 2022 - frontiersin.org
Tumor angiogenesis is one of the most important processes of cancer deterioration via
nurturing an immunosuppressive tumor environment (TME). Targeting tumor angiogenesis …
nurturing an immunosuppressive tumor environment (TME). Targeting tumor angiogenesis …
How glycobiology can help us treat and beat the COVID-19 pandemic
RD Lardone, YC Garay, P Parodi, S de la Fuente… - Journal of Biological …, 2021 - ASBMB
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged during the last
months of 2019, spreading throughout the world as a highly transmissible infectious illness …
months of 2019, spreading throughout the world as a highly transmissible infectious illness …
The anti-proliferative effects of a frankincense extract in a window of opportunity phase ia clinical trial for patients with breast cancer
IVB Valente, D Garcia, A Abbott, L Spruill… - Breast Cancer Research …, 2024 - Springer
Purpose Boswellic acids, active components of frankincense, suppress tumor proliferation in
vitro with a strong clinical trial safety profile in patients with inflammatory diseases. We …
vitro with a strong clinical trial safety profile in patients with inflammatory diseases. We …