Dermatan sulfotransferase Chst14/D4st1, but not chondroitin sulfotransferase Chst11/C4st1, regulates proliferation and neurogenesis of neural progenitor cells

S Bian, N Akyüz, C Bernreuther, G Loers… - Journal of cell …, 2011 - journals.biologists.com
Chondroitin sulfates (CSs) and dermatan sulfates (DSs) are enriched in the
microenvironment of neural stem cells (NSCs) during development and in the adult …

RPTPζ/phosphacan is abnormally glycosylated in a model of muscle–eye–brain disease lacking functional POMGnT1

CA Dwyer, E Baker, H Hu, RT Matthews - Neuroscience, 2012 - Elsevier
Congenital muscular dystrophies (CMDs) with associated brain abnormalities are a group of
disorders characterized by muscular dystrophy and brain and eye abnormalities that are …

Neurons and glia modify receptor protein-tyrosine phosphatase ζ (RPTPζ)/phosphacan with cell-specific O-mannosyl glycans in the developing brain

CA Dwyer, T Katoh, M Tiemeyer… - Journal of Biological …, 2015 - ASBMB
Protein O-mannosylation is a glycan modification that is required for normal nervous system
development and function. Mutations in genes involved in protein O-mannosyl glycosylation …

[PDF][PDF] Chondroitin sulfate proteoglycans in neural development and plasticity

N Maeda, N Fukazawa, M Ishii - Front Biosci, 2010 - article.imrpress.com
Introduction 3. CS proteoglycans and biosynthesis of CS 3.1. Structure of CS proteoglycans
3.2. Biosynthesis and structure of CS 4. Functional significance of structural variation of CS …

Expression of hyaluronan and the hyaluronan-binding proteoglycans neurocan, aggrecan, and versican by neural stem cells and neural cells derived from embryonic …

M Abaskharoun, M Bellemare, E Lau, RU Margolis - Brain research, 2010 - Elsevier
We have examined the expression and localization patterns of hyaluronan and hyaluronan-
binding chondroitin sulfate proteoglycans in neural stem cells and differentiated neural cells …

Structural and functional analysis of chondroitin sulfate proteoglycans in the neural stem cell niche

S Sirko, K Akita, A Von Holst, A Faissner - Methods in enzymology, 2010 - Elsevier
The stem cell niche plays an important role for the maintenance and differentiation of neural
stem/progenitor cells (NSPCs). It is composed of distinct cell types that influence NSCPs by …

Utility and control of proteoglycans in tissue engineering

Z Ferdous, KJ Grande-Allen - Tissue engineering, 2007 - liebertpub.com
This review addresses various methods of integrating proteoglycans (PGs) into the design of
engineered tissues and provides insight for designing tissue-engineered disease models …

Identification of ApoE as an autocrine/paracrine factor that stimulates neural stem cell survival via MAPK/ERK signaling pathway

HT Gan, M Tham, S Hariharan… - Journal of …, 2011 - Wiley Online Library
J. Neurochem.(2011) 117, 565–578. Abstract Neural stem cells (NSCs) are self‐renewing
multipotent cells that undergo symmetric and asymmetric cell division during development of …

Characterization of chondroitin sulfate in stem cells derived from umbilical cord blood in rats

K Nakanishi, K Higashi, T Toida, M Asai - PloS one, 2022 - journals.plos.org
Chondroitin sulfate (CS) and its isomeric variant, dermatan sulfate (DS), are complex
glycosaminoglycans (GAGs) which are ubiquitous components of the extracellular matrix in …

Distinct mechanisms underlying the therapeutic effects of low-molecular-weight heparin and chondroitin sulfate on Parkinson's disease

Q Wang, C Bu, H Wang, B Zhang, Q Chen, D Shi… - International Journal of …, 2024 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder influenced by various factors,
including age, genetics, and the environment. Current treatments provide symptomatic relief …