Poly (ethylene glycol)(PEG) hydrogels are being developed as cell delivery vehicles that
have great potential to improve neuronal replacement therapies. Current research priorities …

Glycosaminoglycans (GAGs) are natural, linear and negatively charged
heteropolysaccharides which are incident in every mammalian tissue. They consist of …

CNS lesions generally result in impaired function because regeneration of the adult CNS of
mammals is poor. A variety of lesion models has been described that serve to further the …

Identification of neural stem and progenitor cells (NPCs) in vitro and in vivo is essential to
the use of developmental and disease models of neurogenesis. The dog is a valuable large …

The heparan sulfate proteoglycan glypican-1, the chondroitin sulfate proteoglycan
phosphacan/RPTP (receptor protein-tyrosine phosphatase)-ζ/β and the extracellular matrix …

Like phosphorylation, protein sumoylation likely represents a dynamic PTM to alter protein
function in support of cell regulatory systems. The broad‐spectrum impact of transient or …

Chondroitin sulfate (CS), a polysaccharide moiety of proteoglycans, is one of the major
components of the extracellular matrix in the central nervous system and is involved in …

The activities of plasma membrane associated sialidase Neu3, total β-glucosidase, CBE-
sensitive β-glucosidase, non-lysosomal β-glucosyl ceramidase GBA2, β-galactosidase, β …

The glycosaminoglycan (GAG) family is characterized by covalently linked repeating
disaccharides forming long unbranched polysaccharide chains. Thus far in higher …

The amygdala integrates and coordinates emotional and autonomic responses. The
genetics that underlie variation in amygdala structure may be coupled to variation in levels …