A critical review on the use of DP4+ in the structural elucidation of natural products: the good, the bad and the ugly. A practical guide
MO Marcarino, S Cicetti, MM Zanardi… - Natural Product …, 2022 - pubs.rsc.org
Covering: 2015 up to the end of 2020 Even in the golden age of NMR, the number of natural
products being incorrectly assigned is becoming larger every day. The use of quantum NMR …
products being incorrectly assigned is becoming larger every day. The use of quantum NMR …
Catellatolactams A–C, Plant Growth-Promoting Ansamacrolactams from a Rare Actinomycete of the Genus Catellatospora
C Liu, Z Zhang, K Fukaya, D Urabe… - Journal of Natural …, 2022 - ACS Publications
Catellatolactams A–C (1–3), three novel ansamacrolactams, were isolated from the culture
extract of an underexplored rare actinomycete of the genus Catellatospora. Spectroscopic …
extract of an underexplored rare actinomycete of the genus Catellatospora. Spectroscopic …
Exploring the diverse landscape of biaryl-containing peptides generated by cytochrome P450 macrocyclases
Cytochrome P450 enzymes (P450s) catalyze diverse oxidative cross-coupling reactions
between aromatic substrates in the natural product biosynthesis. Specifically, P450s install …
between aromatic substrates in the natural product biosynthesis. Specifically, P450s install …
Cytochrome P450Blt Enables Versatile Peptide Cyclisation to Generate Histidine‐ and Tyrosine‐Containing Crosslinked Tripeptide Building Blocks
Y Zhao, E Marschall, M Treisman… - Angewandte Chemie …, 2022 - Wiley Online Library
We report our investigation of the utility of peptide crosslinking cytochrome P450 enzymes
from biarylitide biosynthesis to generate a range of cyclic tripeptides from simple synthons …
from biarylitide biosynthesis to generate a range of cyclic tripeptides from simple synthons …
[PDF][PDF] A biaryl-linked tripeptide from Planomonospora reveals a widespread class of minimal RiPP gene clusters
Microbial natural products impress by their bioactivity, structural diversity, and ingenious
biosynthesis. While screening the less exploited actinobacterial genus Planomonospora …
biosynthesis. While screening the less exploited actinobacterial genus Planomonospora …
P450-modified ribosomally synthesized peptides with aromatic cross-links
YL Hu, FZ Yin, J Shi, SY Ma, ZR Wang… - Journal of the …, 2023 - ACS Publications
Cyclization of linear peptides is an effective strategy to convert flexible molecules into rigid
compounds, which is of great significance for enhancing the peptide stability and bioactivity …
compounds, which is of great significance for enhancing the peptide stability and bioactivity …
Cytochromes P450 involved in bacterial RiPP biosyntheses
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a large
class of secondary metabolites that have garnered scientific attention due to their complex …
class of secondary metabolites that have garnered scientific attention due to their complex …
Development of a drug discovery approach from microbes with a special focus on isolation sources and taxonomy
Y Igarashi - The Journal of Antibiotics, 2023 - nature.com
After the successful discoveries of numerous antibiotics from microorganisms, frequent
reisolation of known compounds becomes an obstacle in further development of new drugs …
reisolation of known compounds becomes an obstacle in further development of new drugs …
Plant growth-promoting and antimicrobial chloropyrroles from a rare actinomycete of the genus Catellatospora
C Liu, H Yamamura, M Hayakawa, Z Zhang… - The Journal of …, 2022 - nature.com
Two new chloropyrroles, designated catellatopyrroles A (1) and B (2), along with 2-(2′-
hydroxybenzoyl) pyrrole (3), were isolated from a culture extract of an actinomycete of the …
hydroxybenzoyl) pyrrole (3), were isolated from a culture extract of an actinomycete of the …
Trehangelin E, a bisacyl trehalose with plant growth promoting activity from a rare actinomycete Polymorphospora sp. RD064483
S Lu, E Harunari, N Oku, Y Igarashi - The Journal of Antibiotics, 2022 - nature.com
Abstract Trehangelin E (1), a new bisacyl trehalose, was isolated from the culture extract of
an actinomycete Polymorphospora sp. RD064483, along with three known congeners …
an actinomycete Polymorphospora sp. RD064483, along with three known congeners …