Neutrophils are the most abundant circulating and first-responding innate myeloid cells and
have so far been underestimated in the context of multiple sclerosis (MS). MS is the most …

Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous
system. Nowadays, available therapies for MS can help to manage MS course and …

Multiple Sclerosis (MS) is, to date, an incurable disease of the nervous system characterized
by demyelination. Several genetic mutations are associated with the disease but they are …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an exceptionally
transmissible and pathogenic coronavirus that appeared at the end of 2019 and triggered a …

Background Numerous studies have demonstrated the role of T helper (Th) 17 and T
regulatory (reg) cells and pro-inflammatory and anti-inflammatory cytokines related to these …

Background and Objectives Epstein-Barr virus (EBV) is a ubiquitous herpesvirus that
establishes lifelong latency in memory B cells and has been identified as a major risk factor …

In this explorative study, we investigated if an adjunctive treatment with one single dose of
the monoclonal antibody rituximab would improve symptoms and function in treatment …

While the contribution of autoreactive CD4+ T cells to the pathogenesis of Multiple Sclerosis
(MS) is widely accepted, the advent of B cell-depleting monoclonal antibody (mAb) therapies …

Multiple sclerosis (MS) is an autoimmune-mediated demyelinating disease of the central
nervous system. The main pathological features are inflammatory reaction, demyelination …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disorder of the central
nervous system. The immunopathology of MS involves both T and B lymphocytes. Rituximab …