Beyond blood: Advancing the frontiers of liquid biopsy in oncology and personalized medicine

Y Bao, D Zhang, H Guo, W Ma - Cancer Science, 2024 - Wiley Online Library
Liquid biopsy is emerging as a pivotal tool in precision oncology, offering a noninvasive and
comprehensive approach to cancer diagnostics and management. By harnessing biofluids …

[HTML][HTML] Molecular pathways and targeted therapies in head and neck cancers pathogenesis

M Constantin, MC Chifiriuc, C Bleotu… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
The substantial heterogeneity exhibited by head and neck cancer (HNC), encompassing
diverse cellular origins, anatomical locations, and etiological contributors, combined with the …

miR-181b-1-3p affects the proliferation and differentiation of chondrocytes in TD broilers through the WIF1/Wnt/β-catenin pathway

Q Sun, S Wu, K Liu, Y Li, K Mehmood, M Nazar… - Pesticide Biochemistry …, 2023 - Elsevier
Thiram is a plant fungicide, its excessive use has exceeded the required environmental
standards. It causes tibial dyschondroplasia (TD) in broilers which is a common metabolic …

MiR-148a-3p Promotes Colorectal Cancer Cell Ferroptosis by Targeting SLC7A11

E Martino, A Balestrieri, F Aragona, G Bifulco, L Mele… - Cancers, 2023 - mdpi.com
Simple Summary The role of miR-148a-3p in colorectal cancer (CRC) is still debated. In this
study, the in vitro antineoplastic effect of miR-148a-3p overexpression in the CRC model is …

The use of tissue-on-chip technology to focus the search for extracellular vesicle miRNA biomarkers in thyroid disease

T Haigh, H Beattie, MA Wade, J England… - International Journal of …, 2023 - mdpi.com
Small extracellular vesicles (sEVs) contain microRNAs (miRNAs) which have potential to act
as disease-specific biomarkers. The current study uses an established method to maintain …

Biomarkers for early cancer detection: A landscape view of recent advancements, spotlighting pancreatic and liver cancers

R Tenchov, AK Sapra, J Sasso, K Ralhan… - ACS Pharmacology & …, 2024 - ACS Publications
Cancer is one of the leading causes of death worldwide. Early cancer detection is critical
because it can significantly improve treatment outcomes, thus saving lives, reducing …

Advances in nucleic acid research: Exploring the potential of oligonucleotides for therapeutic applications and biological studies

M Moccia, B Pascucci, M Saviano, MT Cerasa… - International Journal of …, 2023 - mdpi.com
In recent years, nucleic acids have emerged as powerful biomaterials, revolutionizing the
field of biomedicine. This review explores the multifaceted applications of nucleic acids …

[HTML][HTML] Non-invasive detection of orthotopic human lung tumors by microRNA expression profiling of mouse exhaled breath condensates and exhaled extracellular …

MI Mitchell, IZ Ben-Dov, C Liu, T Wang… - Extracellular vesicles …, 2024 - ncbi.nlm.nih.gov
Aim: The lung is the second most frequent site of metastatic dissemination. Early detection is
key to improving survival. Given that the lung interfaces with the external environment, the …

The role of microRNAs in the gastric cancer tumor microenvironment

X Yu, Y Zhang, F Luo, Q Zhou, L Zhu - Molecular Cancer, 2024 - Springer
Background Gastric cancer (GC) is one of the deadliest malignant tumors with unknown
pathogenesis. Due to its treatment resistance, high recurrence rate, and lack of reliable early …

Epigenetic Downregulation of Hsa-miR-193b-3p Increases Cyclin D1 Expression Level and Cell Proliferation in Human Meningiomas

P Kober, BJ Mossakowska, N Rusetska… - International Journal of …, 2023 - mdpi.com
Meningiomas are common intracranial tumors in adults. Abnormal microRNA (miRNA)
expression plays a role in their pathogenesis. Change in miRNA expression level can be …