Lipid droplets in plants and algae: Distribution, formation, turnover and function

T Ischebeck, HE Krawczyk, RT Mullen, JM Dyer… - Seminars in cell & …, 2020 - Elsevier
Plant oils represent an energy-rich and carbon-dense group of hydrophobic compounds.
These oils are not only of economic interest, but also play important, fundamental roles in …

In vivo imaging with genetically encoded redox biosensors

AI Kostyuk, AS Panova, AD Kokova, DA Kotova… - International journal of …, 2020 - mdpi.com
Redox reactions are of high fundamental and practical interest since they are involved in
both normal physiology and the pathogenesis of various diseases. However, this area of …

[PDF][PDF] The CDC48 complex mediates ubiquitin-dependent degradation of intra-chloroplast proteins in plants

J Li, J Yuan, Y Li, H Sun, T Ma, J Huai, W Yang… - Cell Reports, 2022 - cell.com
Chloroplasts are the site of numerous biochemical reactions including photosynthesis, but
they also produce reactive oxygen species (ROS) that negatively affect chloroplast integrity …

PUX10 is a lipid droplet-localized scaffold protein that interacts with CELL DIVISION CYCLE48 and is involved in the degradation of lipid droplet proteins

FK Kretzschmar, LA Mengel, AO Müller, K Schmitt… - The Plant …, 2018 - academic.oup.com
The number of known proteins associated with plant lipid droplets (LDs) is small compared
with other organelles. Many aspects of LD biosynthesis and degradation are unknown, and …

SVIP is a molecular determinant of lysosomal dynamic stability, neurodegeneration and lifespan

AE Johnson, BO Orr, RD Fetter, AJ Moughamian… - Nature …, 2021 - nature.com
Abstract Missense mutations in Valosin-Containing Protein (VCP) are linked to diverse
degenerative diseases including IBMPFD, amyotrophic lateral sclerosis (ALS), muscular …

Ubiquitin-dependent and independent roles of SUMO in proteostasis

F Liebelt, ACO Vertegaal - American Journal of Physiology …, 2016 - journals.physiology.org
Cellular proteomes are continuously undergoing alterations as a result of new production of
proteins, protein folding, and degradation of proteins. The proper equilibrium of these …

NO signaling in plant immunity: a tale of messengers

P Trapet, A Kulik, O Lamotte, S Jeandroz, S Bourque… - Phytochemistry, 2015 - Elsevier
Nitric oxide (NO) is a free radical gas involved in a myriad of plant physiological processes
including immune responses. How NO mediates its biological effects in plant facing …

VCP-dependent muscle degeneration is linked to defects in a dynamic tubular lysosomal network in vivo

AE Johnson, H Shu, AG Hauswirth, A Tong, GW Davis - elife, 2015 - elifesciences.org
Lysosomes are classically viewed as vesicular structures to which cargos are delivered for
degradation. Here, we identify a network of dynamic, tubular lysosomes that extends …

Nuclear protein quality control in yeast: The latest INQuiries

A Kumar, V Mathew, PC Stirling - Journal of Biological Chemistry, 2022 - ASBMB
The nucleus is a highly organized organelle with an intricate substructure of chromatin,
RNAs, and proteins. This environment represents a challenge for maintaining protein quality …

Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells

Y Morozumi, F Boussouar, M Tan… - Journal of molecular …, 2016 - academic.oup.com
Although the conserved AAA ATPase and bromodomain factor, ATAD2, has been described
as a transcriptional co-activator upregulated in many cancers, its function remains poorly …