Western lifestyle contributes to an overt increase in the prevalence of metabolic anomalies
including diabetes mellitus (DM) and obesity. Prevalence of DM is rapidly growing …

Diabetic kidney disease (DKD) has become the leading cause of end-stage renal disease
(ESRD), and the prevalence of DKD has increased worldwide during recent years. DKD is …

Diabetic nephropathy remains a common cause of end-stage renal failure and its associated
mortality around the world. Sphingosine 1-phosphate (S1P) is a multifunctional lipid …

Ethnopharmacological relevance Diabetes is a common chronic disease. Chinese herbal
medicine (CHM) has a history of several thousand years in the treatment of diabetes, and …

Strong evidence suggests a correlation between degeneration and mitochondrial deficiency.
Typical cases of degeneration can be observed in physiological phenomena (ie, ageing) as …

Diabetic kidney disease (DKD) is a primary cause for end-stage renal disease, but no
specific therapeutic approaches exist. Exosomal miRNAs, a key functional cargo of …

Mitophagy, a mechanism of self-protection against oxidative stress, plays a critical role in
podocyte injury caused by diabetic kidney disease (DKD). Sulforaphane (SFN), an …

Vitamins are micronutrients necessary for the normal function of the body. Although each
vitamin has different physicochemical properties and a specific role in maintaining life, they …

Background CAMK1 has been shown to be involved in human disease progression via
regulating mitochondrial dynamics. However, whether CAMK1 mediates mitochondrial …

Aims Evidence regarding serum methylmalonic acid (MMA) levels and mortality in
individuals with diabetes is limited. This study aimed to evaluate the correlation between …