[HTML][HTML] Activation of microbial secondary metabolic pathways: Avenues and challenges
B Baral, A Akhgari, M Metsä-Ketelä - Synthetic and Systems Biotechnology, 2018 - Elsevier
Microbial natural products are a tremendous source of new bioactive chemical entities for
drug discovery. Next generation sequencing has revealed an unprecedented genomic …
drug discovery. Next generation sequencing has revealed an unprecedented genomic …
Signal Transduction and Regulatory Mechanisms Involved in Control of the σS (RpoS) Subunit of RNA Polymerase
R Hengge-Aronis - Microbiology and molecular biology reviews, 2002 - Am Soc Microbiol
The σS (RpoS) subunit of RNA polymerase is the master regulator of the general stress
response in Escherichia coli and related bacteria. While rapidly growing cells contain very …
response in Escherichia coli and related bacteria. While rapidly growing cells contain very …
Growth Phase-Dependent Variation in Protein Composition of the Escherichia coli Nucleoid
T Ali Azam, A Iwata, A Nishimura, S Ueda… - Journal of …, 1999 - Am Soc Microbiol
The genome DNA of Escherichia coli is associated with about 10 DNA-binding structural
proteins, altogether forming the nucleoid. The nucleoid proteins play some functional roles …
proteins, altogether forming the nucleoid. The nucleoid proteins play some functional roles …
Twelve species of the nucleoid-associated protein from Escherichia coli: sequence recognition specificity and DNA binding affinity
TA Azam, A Ishihama - Journal of Biological Chemistry, 1999 - ASBMB
The genome of Escherichia coli is composed of a single molecule of circular DNA with the
length of about 47,000 kilobase pairs, which is associated with about 10 major DNA-binding …
length of about 47,000 kilobase pairs, which is associated with about 10 major DNA-binding …
Large‐scale monitoring of pleiotropic regulation of gene expression by the prokaryotic nucleoid‐associated protein, H‐NS
F Hommais, E Krin, C Laurent‐Winter… - Molecular …, 2001 - Wiley Online Library
Despite many years of intense work investigating the function of nucleoid‐associated
proteins in prokaryotes, their role in bacterial physiology remains largely unknown. The two …
proteins in prokaryotes, their role in bacterial physiology remains largely unknown. The two …
A divalent switch drives H-NS/DNA-binding conformations between stiffening and bridging modes
Heat-stable nucleoid structuring protein (H-NS) is an abundant prokaryotic protein that plays
important roles in organizing chromosomal DNA and gene silencing. Two controversial …
important roles in organizing chromosomal DNA and gene silencing. Two controversial …
Association of nucleoid proteins with coding and non-coding segments of the Escherichia coli genome
DC Grainger, D Hurd, MD Goldberg… - Nucleic acids …, 2006 - academic.oup.com
The Escherichia coli chromosome is condensed into an ill-defined structure known as the
nucleoid. Nucleoid-associated DNA-binding proteins are involved in maintaining this …
nucleoid. Nucleoid-associated DNA-binding proteins are involved in maintaining this …
Riboregulation in Escherichia coli: DsrA RNA acts by RNA:RNA interactions at multiple loci
RA Lease, ME Cusick, M Belfort - Proceedings of the …, 1998 - National Acad Sciences
DsrA is an 87-nt untranslated RNA that regulates both the global transcriptional silencer and
nucleoid protein H-NS and the stationary phase and stress response sigma factor RpoS …
nucleoid protein H-NS and the stationary phase and stress response sigma factor RpoS …
Multiple control of flagellum biosynthesis in Escherichia coli: role of H-NS protein and the cyclic AMP-catabolite activator protein complex in transcription of the flhDC …
O Soutourina, A Kolb, E Krin… - Journal of …, 1999 - Am Soc Microbiol
Little is known about the molecular mechanism by which histone-like nucleoid-structuring (H-
NS) protein and cyclic AMP-catabolite activator protein (CAP) complex control bacterial …
NS) protein and cyclic AMP-catabolite activator protein (CAP) complex control bacterial …
How do bacteria sense and respond to low temperature?
S Shivaji, JSS Prakash - Archives of microbiology, 2010 - Springer
Rigidification of the membrane appears to be the primary signal perceived by a bacterium
when exposed to low temperature. The perception and transduction of the signal then …
when exposed to low temperature. The perception and transduction of the signal then …