COVID-19 is an infectious disease caused by the coronavirus SARS-CoV-2, which was first
reported in Wuhan, China, in December 2019 and has caused a global pandemic. Acute …

Human immunodeficiency virus type 1 (HIV-1) infection persists despite years of
antiretroviral therapy (ART). To remove the stigma and burden of chronic infection …

Type 1 interferons (IFN-I) are potent innate antiviral effectors that constrain HIV-1
transmission. However, harnessing these cytokines for HIV-1 cure strategies has been …

Functional, tumor-specific CD8+ cytotoxic T lymphocytes drive the adaptive immune
response to cancer. Thus, induction of their activity is the ultimate aim of all …

Although many HIV cure strategies seek to expand HIV-specific CD8+ T cells to control the
virus, all are likely to fail if cellular exhaustion is not prevented. A loss in stem-like memory …

The motive of this work is to find the numerical simulations of a dynamical HIV model along
with the effects of prevention, ie, HIPV nonlinear mathematical system. An advance …

People living with HIV (PLWH), despite suppression of viral replication with antiretroviral
therapy (ART), have high morbidity and mortality due to immune activation and chronic …

Despite the success of antiretroviral therapy (ART), people living with HIV continue to suffer
from high burdens of respiratory infections, lung cancers and chronic lung disease at a …

Summary Background Dysfunction of CD8+ T cells in people living with HIV-1 (PLWH)
receiving anti-retroviral therapy (ART) has restricted the efficacy of dendritic cell (DC)-based …

Despite the development of vaccines, which protect healthy people from severe and life-
threatening Covid-19, the immunological responses of people with secondary …