FOXO3a in cancer drug resistance

Y Liu, Y Wang, X Li, Y Jia, J Wang, X Ao - Cancer Letters, 2022 - Elsevier
Cancer is one of the major causes of death and a significant obstacle to increasing life
expectancy worldwide. Chemotherapy remains the first-line adjuvant therapeutic option for …

8q24. 21 locus: a paradigm to link non-coding RNAs, genome polymorphisms and cancer

C Wilson, A Kanhere - International journal of molecular sciences, 2021 - mdpi.com
The majority of the human genome is comprised of non-protein-coding genes, but the
relevance of non-coding RNAs in complex diseases has yet to be fully elucidated. One class …

microRNA-130b-3p contained in MSC-derived EVs promotes lung cancer progression by regulating the FOXO3/NFE2L2/TXNRD1 axis

Q Guo, J Yan, T Song, C Zhong, J Kuang, Y Mo… - Molecular Therapy …, 2021 - cell.com
This study aimed to explore the molecular mechanism by which mesenchymal stem cells
(MSCs) mediate lung cancer progression. Extracellular vesicles (EVs) were isolated from …

[HTML][HTML] Long noncoding RNA NR2F1-AS1 promotes the malignancy of non-small cell lung cancer via sponging microRNA-493-5p and thereby increasing ITGB1 …

C Zhang, S Wu, R Song, C Liu - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Several studies have reported that the long noncoding ribonucleic acid (lncRNA) NR2F1
antisense RNA 1 (NR2F1-AS1) affects multiple cellular pathways that are involved in …

lncRNA TPTEP1 competitively sponges miR‑328‑5p to inhibit the proliferation of non‑small cell lung cancer cells

F Cao, Z Wang, Y Feng, H Zhu, M Yang… - Oncology …, 2020 - spandidos-publications.com
Accumulating evidence suggests that lncRNAs are involved in almost all normal
physiological processes and that aberrant expression of lncRNAs may be involved in the …

CASC11 promotes aggressiveness of prostate cancer cells through miR-145/IGF1R axis

O Capik, F Sanli, A Kurt, O Ceylan, I Suer… - Prostate cancer and …, 2021 - nature.com
Abstract Background Prostate cancer (PCa) is the most common malignancy diagnosed
among men after lung cancer in developed countries. Investigation of the underlying …

[HTML][HTML] A circGLIS3/miR-644a/PTBP1 positive feedback loop promotes the malignant biological progressions of non-small cell lung cancer

Z Wu, H Jiang, H Fu, Y Zhang - American Journal of Cancer …, 2021 - ncbi.nlm.nih.gov
Non-small cell lung cancer (NSCLC) is a severe cancer which critically threatens human
health in the world. Circular RNAs (circRNAs) are non-coding RNAs that involve in cancer …

RETRACTED ARTICLE: Hsa_circ_RNA_0011780 Represses the Proliferation and Metastasis of Non-Small Cell Lung Cancer by Decreasing FBXW7 via Targeting …

Y Liu, C Yang, C Cao, Q Li, X Jin, H Shi - OncoTargets and therapy, 2020 - Taylor & Francis
At the authors request, the Editor and Publisher of OncoTargets and Therapy wish to retract
the published article. The authors became aware of concerns which had been raised …

[HTML][HTML] Long non-coding RNA LINC01480 is activated by Foxo3a and promotes hydroquinone-induced TK6 cell apoptosis by inhibiting the PI3K/AKT pathway

H Yang, Y Chen, M Zeng, H Wu, X Zou, T Fang… - Ecotoxicology and …, 2023 - Elsevier
Long non-coding RNAs (lncRNAs) have been shown to play a critical role in the damage
caused to the body by environmental exogenous chemicals; however, few studies have …

[HTML][HTML] Unveiling the potential of FOXO3 in lung cancer: From molecular insights to therapeutic prospects

M Ebrahimnezhad, A Valizadeh, M Majidinia… - Biomedicine & …, 2024 - Elsevier
Lung cancer poses a significant challenge regarding molecular heterogeneity, as it
encompasses a wide range of molecular alterations and cancer-related pathways. Recent …