Objectives Over the past decades, many studies focused on mesenchymal stem cells
(MSCs) therapy for bone regeneration. Due to the efficiency of topical application has been …

Bone tissue engineering (BTE) is a promising approach for repairing and regenerating
damaged bone tissue, using stem cells and scaffold structures. Among various stem cell …

The craniofacial area is prone to trauma or pathologies often resulting in large bone
damages. One potential treatment option is the grafting of a tissue-engineered construct …

The extracellular matrix is a dynamic and active component of the mesenchymal stem cell
niche, which controls their differentiation and self-renewal. Traditional in vitro culture …

Stem cells endowed with skeletogenic potentials seeded in specific scaffolds are considered
attractive tissue engineering strategies for treating large bone defects. In the context of …

Periodontal disease (PD) is one of the main causes of periodontal bone resorption and tooth
loss in adults. How to repair the alveolar bone effectively has always been a challenge. This …

Introduction: The ability to resolve pulpal inflammation to achieve predictable regeneration
of the dentin-pulp complex has remained elusive and presents a challenge for clinicians and …

Therapies using stem cells may be applicable to all fields of regenerative medicine,
including craniomaxillofacial surgery. Dental pulp stem cells (DPSCs) have demonstrated in …

The mechanisms involved in local induced inflammation can be studied using several
available animal models. One of these is the induction of apical periodontitis (AP). Apical …

Hypoxic preconditioning is commonly applied to enhance mesenchymal stem cells (MSCs)
therapeutic effect before transplantation. Elucidating the effect of hypoxic preconditioning …