The secretion profile of mesenchymal stem cells and potential applications in treating human diseases

Y Han, J Yang, J Fang, Y Zhou, E Candi… - … and Targeted Therapy, 2022 - nature.com
Mesenchymal stromal/stem cells (MSCs) possess multi-lineage differentiation and self-
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …

Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Mesenchymal stem/stromal cells as a valuable source for the treatment of immune-mediated disorders

A Markov, L Thangavelu, S Aravindhan… - Stem cell research & …, 2021 - Springer
Over recent years, mesenchymal stem/stromal cells (MSCs) and their potential biomedical
applications have received much attention from the global scientific community in an …

Stromal cells in the tumor microenvironment: accomplices of tumor progression?

Y Zhao, M Shen, L Wu, H Yang, Y Yao, Q Yang… - Cell Death & …, 2023 - nature.com
The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular
component), and cellular components include cancer cells and non-malignant cells such as …

The osteosarcoma microenvironment: a complex but targetable ecosystem

I Corre, F Verrecchia, V Crenn, F Redini, V Trichet - Cells, 2020 - mdpi.com
Osteosarcomas are the most frequent primary bone sarcomas, affecting mainly children,
adolescents, and young adults, and with a second peak of incidence in elderly individuals …

Biological functions of mesenchymal stem cells and clinical implications

A Naji, M Eitoku, B Favier, F Deschaseaux… - Cellular and Molecular …, 2019 - Springer
Mesenchymal stem cells (MSCs) are isolated from multiple biological tissues—adult bone
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …

Mesenchymal stromal cell homing: mechanisms and strategies for improvement

M Ullah, DD Liu, AS Thakor - Iscience, 2019 - cell.com
Mesenchymal stromal cells (MSCs) have been widely investigated for their therapeutic
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …

Repair and tissue engineering techniques for articular cartilage

EA Makris, AH Gomoll, KN Malizos, JC Hu… - Nature Reviews …, 2015 - nature.com
Chondral and osteochondral lesions due to injury or other pathology commonly result in the
development of osteoarthritis, eventually leading to progressive total joint destruction …

[HTML][HTML] Integrated gradient tissue-engineered osteochondral scaffolds: Challenges, current efforts and future perspectives

X Niu, N Li, Z Du, X Li - Bioactive Materials, 2023 - Elsevier
The osteochondral defect repair has been most extensively studied due to the rising
demand for new therapies to diseases such as osteoarthritis. Tissue engineering has been …

[HTML][HTML] Homing and migration of mesenchymal stromal cells: how to improve the efficacy of cell therapy?

A De Becker, I Van Riet - World journal of stem cells, 2016 - ncbi.nlm.nih.gov
Mesenchymal stromal cells (MSCs) are currently being investigated for use in a wide variety
of clinical applications. For most of these applications, systemic delivery of the cells is …