Cancer is a major health issue worldwide, and the global burden of cancer is expected to
increase in the coming years. Whereas the limited success with current therapies has driven …

Liposarcomas are rare malignant tumors of adipocytic differentiation. The classification of
liposarcomas into four principal subtypes reflects the distinct clinical behavior, treatment …

Once melanomas have progressed with acquired resistance to mitogen-activated protein
kinase (MAPK)-targeted therapy, mutational heterogeneity presents a major challenge. We …

The present review discusses recent work on melatonin-mediated circadian regulation, the
metabolic and molecular signaling mechanisms that are involved in human breast cancer …

Drug repositioning (also referred to as drug repurposing), the process of finding new uses of
existing drugs, has been gaining popularity in recent years. The availability of several …

Retroperitoneal liposarcoma (RLS) is a rare, biologically heterogeneous tumor that present
considerable challenges due to its size and deep location. As a consequence, the majority …

Well-differentiated liposarcoma (WDL) and dedifferentiated liposarcoma (DDL) form the
largest subgroup of liposarcomas, and represent a morphologic and behavioral spectrum of …

Cancer poses a significant global health challenge, with predictions of increasing
prevalence in the coming years due to limited prevention, late diagnosis, and inadequate …

Sarcomas are a heterogeneous group of mesenchymal tumors arising from soft tissue or
bone, with an uncertain etiology and difficult classification. Soft tissue sarcomas (STSs) …

Simple Summary To this day, cancer remains a medical challenge despite the development
of cutting-edge diagnostic methods and therapeutics. Thus, there is a continual demand for …