Phosphoinositides in new spaces
EM Davies, CA Mitchell… - Cold Spring Harbor …, 2023 - cshperspectives.cshlp.org
Phosphoinositides (PIs) are phospholipids derived from phosphatidylinositol. PIs are
regulated via reversible phosphorylation, which is directed by the opposing actions of PI …
regulated via reversible phosphorylation, which is directed by the opposing actions of PI …
The mechanisms of class 1A PI3K and Wnt/β-catenin coupled signaling in breast cancer
SJ Rodgers, CA Mitchell… - Biochemical Society …, 2023 - portlandpress.com
The class IA PI3K signaling pathway is activated by growth factor stimulation and regulates a
signaling cascade that promotes diverse events including cell growth, proliferation …
signaling cascade that promotes diverse events including cell growth, proliferation …
Restoration of corneal epithelial barrier function: a possible target for corneal neovascularization
S Shen, Y Zhang - The Ocular Surface, 2024 - Elsevier
Corneal neovascularization (CoNV) is the second leading common cause of vision
impairment worldwide and is a blinding pathological alteration brought on by ocular trauma …
impairment worldwide and is a blinding pathological alteration brought on by ocular trauma …
[HTML][HTML] Loss of INPP5K attenuates IP3-induced Ca2+ responses in the glioblastoma cell line U-251 MG cells
J Loncke, T Luyten, AR Ramos, C Erneux, G Bultynck - BBA advances, 2023 - Elsevier
Abstract INPP5K (inositol polyphosphate 5-phosphatase K) is an endoplasmic reticulum
(ER)-resident enzyme that acts as a phosphoinositide (PI) 5-phosphatase, capable of …
(ER)-resident enzyme that acts as a phosphoinositide (PI) 5-phosphatase, capable of …
[HTML][HTML] Targeting PKM2 signaling cascade with salvianic acid A normalizes tumor blood vessels to facilitate chemotherapeutic drug delivery
C Qian, Y Zhou, T Zhang, G Dong, M Song… - … Pharmaceutica Sinica B, 2024 - Elsevier
Aberrant tumor blood vessels are prone to propel the malignant progression of tumors, and
targeting abnormal metabolism of tumor endothelial cells emerges as a promising option to …
targeting abnormal metabolism of tumor endothelial cells emerges as a promising option to …