A systematic review on biomarker identification for cancer diagnosis and prognosis in multi-omics: from computational needs to machine learning and deep learning

A Dhillon, A Singh, VK Bhalla - Archives of Computational Methods in …, 2023 - Springer
Biomarkers, also known as biological markers, are substances like transcripts,
deoxyribonucleic acid (DNA), genes, proteins, and metabolites that indicate whether a …

Incorporating machine learning into established bioinformatics frameworks

N Auslander, AB Gussow, EV Koonin - International journal of molecular …, 2021 - mdpi.com
The exponential growth of biomedical data in recent years has urged the application of
numerous machine learning techniques to address emerging problems in biology and …

Computational oncology in the multi-omics era: state of the art

G de Anda-Jáuregui, E Hernández-Lemus - Frontiers in oncology, 2020 - frontiersin.org
Cancer is the quintessential complex disease. As technologies evolve faster each day, we
are able to quantify the different layers of biological elements that contribute to the …

Computational techniques and tools for omics data analysis: state-of-the-art, challenges, and future directions

P Kaur, A Singh, I Chana - Archives of Computational Methods in …, 2021 - Springer
The heterogeneous and high-dimensional nature of omics data presents various challenges
in gaining insights while analysis. In the era of big data, omics data is available as genome …

Toward a standardized strategy of clinical metabolomics for the advancement of precision medicine

NP Long, TD Nghi, YP Kang, NH Anh, HM Kim… - Metabolites, 2020 - mdpi.com
Despite the tremendous success, pitfalls have been observed in every step of a clinical
metabolomics workflow, which impedes the internal validity of the study. Furthermore, the …

Diagnostic accuracy of blood-based biomarkers for pancreatic cancer: a systematic review and meta-analysis

LE Kane, GS Mellotte, E Mylod, RM O'Brien… - Cancer research …, 2022 - AACR
Pancreatic ductal adenocarcinoma (PDAC) has a 5-year survival rate below 5%.
Carbohydrate antigen 19-9 (CA19-9) is the most commonly used blood-based biomarker for …

Chromogranin-A expression as a novel biomarker for early diagnosis of colon cancer patients

X Zhang, H Zhang, B Shen, XF Sun - International journal of molecular …, 2019 - mdpi.com
Colon cancer is one of the major causes of cancer death worldwide. The five-year survival
rate for the early-stage patients is more than 90%, and only around 10% for the later stages …

Automated classification of urine biomarkers to diagnose pancreatic cancer using 1-D convolutional neural networks

ME Karar, N El-Fishawy, M Radad - Journal of Biological Engineering, 2023 - Springer
Abstract Background Early diagnosis of Pancreatic Ductal Adenocarcinoma (PDAC) is the
main key to surviving cancer patients. Urine proteomic biomarkers which are creatinine …

[Retracted] Application of Artificial Intelligence in Discovery and Development of Anticancer and Antidiabetic Therapeutic Agents

A Alqahtani - Evidence‐Based Complementary and Alternative …, 2022 - Wiley Online Library
Spectacular developments in molecular and cellular biology have led to important
discoveries in cancer research. Despite cancer is one of the major causes of morbidity and …

Mining prognosis index of brain metastases using artificial intelligence

S Huang, J Yang, S Fong, Q Zhao - Cancers, 2019 - mdpi.com
This study is to identify the optimum prognosis index for brain metastases by machine
learning. Seven hundred cancer patients with brain metastases were enrolled and divided …