Prognostic value of intrathecal IgM synthesis determined by various laboratory methods in patients with early multiple sclerosis-a prospective observational study

K Revendova, D Zeman, P Kusnierova… - Multiple Sclerosis and …, 2022 - Elsevier
Abstract Background Intrathecal IgM synthesis has been identified as an adverse prognostic
factor in patients with multiple sclerosis (MS); however, some studies have not confirmed this …

[HTML][HTML] The novel multiple sclerosis susceptibility gene ATXN1 regulates B cell receptor signaling in B-1a cells

Q Ma, A Didonna - Molecular Brain, 2021 - Springer
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous
system (CNS) caused by complex gene-environment interactions. ATXN1 maps to 6p22. 3 …

Cerebrospinal fluid oligoclonal IgM test in routine practice: Comparison with quantitative assessment of intrathecal IgM synthesis

D Zeman, P Kušnierová, F Všianský, K Reguliová… - Clinica Chimica …, 2020 - Elsevier
Abstract Background Intrathecal IgM synthesis demonstrated either as cerebrospinal fluid
(CSF)-restricted oligoclonal (o-) IgM bands or calculated using various formulas has been …

[HTML][HTML] Assessing the presence of oligoclonal IgM bands as a prognostic biomarker of cognitive decline in the early stages of multiple sclerosis

C Coll‐Martinez, E Quintana, J Salavedra‐Pont… - Brain and …, 2021 - ncbi.nlm.nih.gov
Background An association has been found between the presence of lipid‐specific
oligoclonal IgM bands (LS‐OCMB) in cerebrospinal fluid and a more severe clinical multiple …

[HTML][HTML] Berlin Registry of Neuroimmunological entities (BERLimmun): protocol of a prospective observational study

PS Sperber, AU Brandt, HG Zimmermann, LS Bahr… - BMC neurology, 2022 - Springer
Background Large-scale disease overarching longitudinal data are rare in the field of
neuroimmunology. However, such data could aid early disease stratification, understanding …

Cerebrospinal fluid testing for multiple sclerosis

JF Goldsmith, AZ Herskovits - Clinics in Laboratory Medicine, 2020 - labmed.theclinics.com
Multiple sclerosis (MS) is one of the most common autoimmune diseases affecting the
central nervous system (CNS). It is estimated that more than 2 million people worldwide …

Biomarker zur Abschätzung der Prognose und Diagnose der Multiplen Sklerose

C Korsukewitz, H Wiendl - InFo Neurologie+ Psychiatrie, 2023 - Springer
Bei der Multiplen Sklerose ist die frühe Diagnose und Prognoseabschätzung eine wichtige
Voraussetzung für eine möglichst frühe und gezielte effektive Therapie. Auch wenn kein …

Untersuchungen zu Biomarkern im Liquor und Serum bei neuroimmunologischen und neurovirologischen Erkrankungen

C Otto - 2023 - refubium.fu-berlin.de
Bei der Multiplen Sklerose (MS) handelt es sich um eine chronisch-entzündliche,
demyelinisierende Erkrankung des zentralen Nervensystems. Sie stellt die häufigste …

[PDF][PDF] Factores pronósticos en el síndrome clínico aislado de origen desmielinizante

LL Ballester, BC Estruch, FCP Miralles - 2023 - webges.uv.es
La esclerosis múltiple (EM) es una enfermedad inflamatoria desmielinizante crónica del
sistema nervioso central (SNC), que afecta en la mayoría de los casos a adultos jóvenes, y …

Elucidating Neuroinflammation in Multiple Sclerosis by Network Analysis

NC Welsh - 2024 - digitalcommons.dartmouth.edu
Multiple sclerosis (MS) is a heterogeneous disease, differing on many variables, including
disease course, sex, and overall activity. Key characteristics of the disease encompass …